CN106383503A - Stem cell preparation production process transfer control system based on IOT - Google Patents
Stem cell preparation production process transfer control system based on IOT Download PDFInfo
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Abstract
本发明公开了一种基于物联网的干细胞制剂生产流程传输控制系统,包括多个干细胞制剂处理区间、运输单元、由计算机和手机组成的用户管理设备和系统服务器,系统服务器用于接收物联网运营数据反馈至用户管理端,所述物联终端包括安装在运输单元上,并用于监测干细胞制剂生产的传感器、用于发送信号的通信终端、用于控制传感器和通信终端的主控制器以及用于显示信息的显示屏,所述传感器、通信终端、显示屏均与主控制器电连接,还包括现场电子看板,现场电子看板安装在生产车间并用于显示物联终端的工作信息。本发明提供的数据信息采集、处理和管理功能自动化程度高、过程管理即时化和智能化的干细胞制剂生产流程传输控制系统。
The invention discloses a stem cell preparation production process transmission control system based on the Internet of Things, which includes a plurality of stem cell preparation processing sections, a transportation unit, user management equipment composed of computers and mobile phones, and a system server. The system server is used to receive Internet of Things operations. The data is fed back to the user management terminal. The IoT terminal includes sensors installed on the transport unit for monitoring the production of stem cell preparations, a communication terminal for sending signals, a master controller for controlling the sensors and communication terminals, and a sensor for monitoring the production of stem cell preparations. The display screen for displaying information, the sensor, communication terminal, and display screen are all electrically connected to the main controller, and also includes an on-site electronic kanban, which is installed in the production workshop and used to display the work information of the IoT terminal. The present invention provides a stem cell preparation production process transmission control system with high automation of data information collection, processing and management functions, instant process management and intelligence.
Description
技术领域technical field
本发明属于生产流程传输技术领域,尤其涉及一种基于物联网的干细胞制剂生产流程传输控制系统。The invention belongs to the technical field of production process transmission, and in particular relates to a production process transmission control system for stem cell preparations based on the Internet of Things.
背景技术Background technique
物联网的英文名称为"The Internet of Things”,简称:IOT。物联网的核心和基础是互联网,是在互联网基础之上的延伸和扩展的一种网络。其用户端延伸和扩展到了任何物品与物品之间进行信息交换和通信。信息传感设备按约定的协议,把任何物品与互联网相连接,进行信息交换和通信,以实现智能化识别、定位、跟踪、监控和管理的一种网络概念。物联网技术的广泛应用是IT时代的产业升级,实现跨设备、跨平台的应用。新技术革命的到来,世界进入信息时代。在利用信息的过程中,首先要解决的就是要获取准确可靠信息,而传感器是获取自然和生产领域中信息的主要途径与手段。现代科学技术的发展也离不开传感器,传感器可以帮助获得新机理和高灵敏度的检测数据。各种复杂的工程系统,大部分的现代化项目都离不开传感器。The English name of the Internet of Things is "The Internet of Things", referred to as: IOT. The core and foundation of the Internet of Things is the Internet, which is a network that extends and expands on the basis of the Internet. Its client end extends and expands to exchange information and communicate between any item. Information sensing equipment connects any item to the Internet according to the agreed protocol for information exchange and communication to realize a network concept of intelligent identification, positioning, tracking, monitoring and management. The wide application of IoT technology is an industrial upgrade in the IT era, realizing cross-device and cross-platform applications. With the advent of the new technological revolution, the world has entered the information age. In the process of using information, the first thing to solve is to obtain accurate and reliable information, and sensors are the main ways and means to obtain information in the natural and production fields. The development of modern science and technology is also inseparable from sensors, which can help to obtain new mechanism and high-sensitivity detection data. Various complex engineering systems, most modern projects are inseparable from sensors.
在生物技术的发展过程中,备受关注的为干细胞相关研发或应用,然而在研发的过程里,如何运送干细胞制剂、成品或半成品却是一件不被大众关注而影响技术成败的关键因素。在干细胞技术研发过程中,需要在不同的实验环境中经过多道不同的处理,例如萃取、分离、纯化或增殖等处理步骤,但在现有技术中由于各个实验环境设置位置的因素,导致干细胞制剂需要在不同的运送环境中移动传输,环境的变化影响干细胞制剂的保存及有效性,容易使珍贵的干细胞制剂材料付之一炬,且为维持适当的干细胞制剂生产流程传输环境往往需要负担高额的成本,因此,需要提供一种有效率的干细胞制剂生产流程传输系统来解决上述的问题。In the development process of biotechnology, stem cell-related R&D or application has received much attention. However, in the R&D process, how to deliver stem cell preparations, finished products or semi-finished products is a key factor that is not paid attention to by the public and affects the success of the technology. In the process of research and development of stem cell technology, it is necessary to undergo multiple different treatments in different experimental environments, such as extraction, separation, purification or proliferation. However, in the prior art, due to the location of each experimental environment, stem cells Preparations need to be moved and transported in different delivery environments. Changes in the environment affect the preservation and effectiveness of stem cell preparations, and it is easy to burn precious stem cell preparation materials. In order to maintain an appropriate production process for stem cell preparations, it is often necessary to bear high costs. Therefore, it is necessary to provide an efficient stem cell preparation production process delivery system to solve the above problems.
综上所述,目前的干细胞制剂生产流程传输控制系统数据信息采集、处理和管理功能自动化程度低、过程管理不能即时化和智能化,干细胞制剂联网智能生产线过程不能有效控制。To sum up, the current stem cell preparation production process transmission control system has a low degree of automation in data information collection, processing and management functions, and the process management cannot be instant and intelligent, and the process of the stem cell preparation networked intelligent production line cannot be effectively controlled.
发明内容Contents of the invention
本发明的目的在于提供一种基于物联网的干细胞制剂生产流程传输控制系统,旨在解决目前的干细胞制剂生产流程传输控制系统数据信息采集、处理和管理功能自动化程度低、过程管理不能即时化和智能化,干细胞制剂联网智能生产线过程不能有效控制的问题。The purpose of the present invention is to provide a stem cell preparation production process transmission control system based on the Internet of Things, aiming to solve the problem of low automation of data information collection, processing and management functions of the current stem cell preparation production process transmission control system, process management can not be real-time Intelligentization, the problem that the stem cell preparation networking intelligent production line process cannot be effectively controlled.
本发明是这样实现的,一种基于物联网的干细胞制剂生产流程传输控制系统,包括多个干细胞制剂处理区间、运输单元、由计算机和手机组成的客户管理端和系统服务器,系统服务器用于接收物联网运营数据反馈至客户管理端,其特征在于:还包括无线wifi路由器和物联终端,所述系统服务器和物联终端之间通过无线wifi路由器传输数据,所述物联终端包括安装在运输单元上,并用于监测干细胞制剂生产的传感器、用于发送信号的通信终端、用于控制传感器和通信终端的主控制器以及用于显示信息的显示屏,所述传感器、通信终端、显示屏均与主控制器电连接,还包括现场电子看板,所述现场电子看板安装在生产车间并用于显示物联终端的工作信息。The present invention is realized in this way, a stem cell preparation production process transmission control system based on the Internet of Things, including a plurality of stem cell preparation processing sections, a transport unit, a client management terminal and a system server composed of computers and mobile phones, and the system server is used to receive The operation data of the Internet of Things is fed back to the customer management terminal, and it is characterized in that it also includes a wireless wifi router and a terminal of the Internet of Things, and data is transmitted between the system server and the terminal of the Internet of Things through a wireless wifi router. on the unit, and sensors for monitoring the production of stem cell preparations, a communication terminal for sending signals, a main controller for controlling the sensors and communication terminals, and a display screen for displaying information, the sensors, communication terminals, display screens are all It is electrically connected with the main controller, and also includes an on-site electronic kanban, which is installed in the production workshop and used to display the work information of the IoT terminal.
进一步,所述干细胞制剂处理区间与所述运输单元间有一配合方式,该配合方式为每个所述干细胞制剂处理区间前后皆各连接或相邻一所述干细胞制剂处理区间,使所述多个干细胞制剂处理区间形成一长条状排列状态。Further, there is a cooperation method between the stem cell preparation treatment section and the transport unit, the cooperation method is that each of the stem cell preparation treatment sections is connected to or adjacent to one of the stem cell preparation treatment sections, so that the multiple The stem cell preparation treatment section forms a long strip arrangement state.
进一步,所述干细胞制剂处理区间可由一环境维持装置维持所述干细胞制剂材料工艺步骤需控制的环境因素。Further, the stem cell preparation treatment section can use an environment maintenance device to maintain the environmental factors that need to be controlled in the process steps of the stem cell preparation material.
进一步,所述运输装置及所述干细胞制剂处理区间分别与控制模块相连,所述控制模块接收由所述干细胞制剂处理区间输出的传递信号Further, the transportation device and the stem cell preparation processing section are respectively connected to a control module, and the control module receives the transmission signal output from the stem cell preparation processing section
进一步,所述运输装置为一自动化机械手臂,所述控制模块依据所述传递信号控制所述自动化机械手臂,所述机械化自动手臂设置于所述干细胞制剂处理区间或运输空间中。Further, the transportation device is an automatic robot arm, the control module controls the automatic robot arm according to the transmission signal, and the mechanized automatic arm is set in the stem cell preparation processing section or transportation space.
进一步,所述物联终端内设置有用于记录干细胞制剂材料的设备管理模块,所述设备管理模块与主控制器连接,所述设备管理模块所记录的信息通过传感器反馈至用户管理端。Further, the IoT terminal is provided with an equipment management module for recording stem cell preparation materials, the equipment management module is connected to the main controller, and the information recorded by the equipment management module is fed back to the user management terminal through sensors.
进一步,所述物联终端内设置有用于进行有效性验证检查模块,所述检查模块与主控制器连接。Further, the IoT terminal is provided with a validity verification and checking module, and the checking module is connected with the main controller.
进一步,所述物联终端内设置有用于对干细胞制剂生产的操作人员进行身份识别的身份识别模块,所述身份识别模块与主控制器连接。Further, an identification module for identifying the operator of stem cell preparation production is provided in the IoT terminal, and the identification module is connected with the main controller.
与现有技术相比,本发明的有益效果是:1、物联终端进行信息采集并通过无线网络发送至系统服务器,系统服务器将所接受的信息转发给用户管理端,管理人员接受信息后只需根据情况发送预定的执行指令完成物联终端各个设备的正常工作、维护维修等一系列功能的实现,实现了过程管理的即时化和智能化;2、设备模块一方面可以将物联终端的信息快速的采集、上传,保证管理人员能够及时作出正确的处理,另一方面可以将信息通过物联网传递展示在生产车间现场的电子看屏上,方便操作工人对对设备终端的正常操作;3、身份识别模块用于对设备终端的操作人员进行身份识别,通过刷卡开机等验证操作人员的资质,确保对设备终端的安全使用;4、该干细胞制剂处理区间与该运输单元可依工艺需求有不同的配合方式,具有较大的工艺弹性;5、该运输单元的运输环境运送,该运输环境由该环境控制装置控制,使该干细胞制剂材料于运送中保持其活性、稳定度或避免裂解。Compared with the prior art, the beneficial effects of the present invention are: 1. The IoT terminal collects information and sends it to the system server through the wireless network, and the system server forwards the received information to the user management terminal. It is necessary to send predetermined execution instructions according to the situation to complete the realization of a series of functions such as normal work, maintenance and repair of each equipment of the IoT terminal, and realize the instant and intelligent process management; 2. On the one hand, the equipment module can integrate the IoT terminal The rapid collection and upload of information ensures that managers can make correct processing in a timely manner. On the other hand, the information can be transmitted and displayed on the electronic screen in the production workshop through the Internet of Things, which is convenient for operators to operate the equipment terminal normally; 3 . The identity recognition module is used to identify the operator of the equipment terminal, and verify the qualification of the operator by swiping the card to start the machine, so as to ensure the safe use of the equipment terminal; Different matching methods have greater process flexibility; 5. The transport environment of the transport unit is transported, and the transport environment is controlled by the environmental control device, so that the stem cell preparation material maintains its activity, stability or avoids cracking during transport.
附图说明Description of drawings
图1是本发明实施例提供的基于物联网的干细胞制剂生产流程传输控制系统结构示意图。Fig. 1 is a schematic structural diagram of the transmission control system for the production process of stem cell preparations based on the Internet of Things provided by the embodiment of the present invention.
图中:1、细胞制剂处理区间;2、运输单元;3、客户管理端;4、系统服务器;5、物联终端;6、设备管理模块;7、身份识别模块;8、检查模块。In the figure: 1. Cell preparation processing section; 2. Transport unit; 3. Client management terminal; 4. System server; 5. IoT terminal; 6. Equipment management module; 7. Identity recognition module; 8. Inspection module.
具体实施方式detailed description
为了使本发明的目的、技术方案及优点更加清楚明白,以下结合实施例,对本发明进行进一步详细说明。应当理解,此处所描述的具体实施例仅仅用以解释本发明,并不用于限定本发明。In order to make the object, technical solution and advantages of the present invention more clear, the present invention will be further described in detail below in conjunction with the examples. It should be understood that the specific embodiments described here are only used to explain the present invention, not to limit the present invention.
下面结合附图对本发明的应用原理作详细描述。The application principle of the present invention will be described in detail below in conjunction with the accompanying drawings.
如图1所示,本发明实施例提供的基于物联网的干细胞制剂生产流程传输控制系统包括多个干细胞制剂处理区间1、运输单元2;由计算机和手机组成的客户管理端3和系统服务器4,系统服务器用于接收物联网运营数据反馈至客户管理端3,还包括无线wifi路由器和物联终端5,所述系统服务器和物联终端之间通过无线wifi路由器传输数据,所述物联终端包括安装在运输单元上,并用于监测干细胞制剂生产的传感器、用于发送信号的通信终端、用于控制传感器和通信终端的主控制器以及用于显示信息的显示屏,所述传感器、通信终端、显示屏均与主控制器电连接,还包括现场电子看板,所述现场电子看板安装在生产车间并用于显示物联终端的工作信息。As shown in Figure 1, the Internet of Things-based stem cell preparation production process transmission control system provided by the embodiment of the present invention includes a plurality of stem cell preparation processing sections 1, a transportation unit 2; a client management terminal 3 and a system server 4 composed of computers and mobile phones , the system server is used to receive the Internet of Things operation data to feed back to the client management terminal 3, and also includes a wireless wifi router and an IoT terminal 5, and the system server and the IoT terminal transmit data through a wireless wifi router, and the IoT terminal Comprising sensors installed on the transport unit and used to monitor the production of stem cell preparations, a communication terminal for sending signals, a main controller for controlling the sensors and communication terminals, and a display screen for displaying information, the sensors, communication terminals , and the display screens are all electrically connected to the main controller, and also include an on-site electronic kanban, which is installed in the production workshop and used to display the work information of the IoT terminal.
进一步,所述干细胞制剂处理区间与所述运输单元间有一配合方式,该配合方式为每个所述干细胞制剂处理区间前后皆各连接或相邻一所述干细胞制剂处理区间,使所述多个干细胞制剂处理区间形成一长条状排列状态。Further, there is a cooperation method between the stem cell preparation treatment section and the transport unit, the cooperation method is that each of the stem cell preparation treatment sections is connected to or adjacent to one of the stem cell preparation treatment sections, so that the multiple The stem cell preparation treatment section forms a long strip arrangement state.
进一步,所述干细胞制剂处理区间可由一环境维持装置维持所述干细胞制剂材料工艺步骤需控制的环境因素。Further, the stem cell preparation treatment section can use an environment maintenance device to maintain the environmental factors that need to be controlled in the process steps of the stem cell preparation material.
进一步,所述运输装置及所述干细胞制剂处理区间分别与控制模块相连,所述控制模块接收由所述干细胞制剂处理区间输出的传递信号Further, the transportation device and the stem cell preparation processing section are respectively connected to a control module, and the control module receives the transmission signal output from the stem cell preparation processing section
进一步,所述运输装置为一自动化机械手臂,所述控制模块依据所述传递信号控制所述自动化机械手臂,所述机械化自动手臂设置于所述干细胞制剂处理区间或运输空间中。Further, the transportation device is an automatic robot arm, the control module controls the automatic robot arm according to the transmission signal, and the mechanized automatic arm is set in the stem cell preparation processing section or transportation space.
进一步,所述物联终端内设置有用于记录干细胞制剂材料的设备管理模块5,所述设备管理模块与主控制器连接,所述设备管理模块6所记录的信息通过传感器反馈至用户管理端。Further, the IoT terminal is provided with an equipment management module 5 for recording stem cell preparation materials, the equipment management module is connected to the main controller, and the information recorded by the equipment management module 6 is fed back to the user management terminal through sensors.
进一步,所述物联终端内设置有用于进行有效性验证检查模块8,所述检查模块与主控制器连接。Further, the IoT terminal is provided with a checking module 8 for validity verification, and the checking module is connected with the main controller.
进一步,所述物联终端内设置有用于对干细胞制剂生产的操作人员进行身份识别的身份识别模块,所述身份识别模块7与主控制器连接。Further, an identification module for identifying the operator of stem cell preparation production is provided in the IoT terminal, and the identification module 7 is connected to the main controller.
下面结合工作原理对本发明作进一步描述。The present invention will be further described in conjunction with the working principle below.
本发明工作时:操作工人到达工作岗位,身份识别卡允许操作人员打开系统授权其使用干细胞制剂的加工设备(未经授权的无法开机);开机后安装在干细胞制剂生产设备上的物联网终端显示屏提示安全生产注意事项、操作规程并自动接收任务指令、自动调用工序对应的作业指导书;然后终端设备以多媒体方式提示做“作业前验证”,包括环境安全健康方面的要求和质量管理的要求,逐项确认后方可进入下一步;干细胞制剂处理区间及该运输空间中有一交换空间,该交换空间作为该干细胞制剂处理区间与该运输空间中的环境缓冲,避免该干细胞制剂材料于运输过程中产生过大的环境差异,例如在该干细胞制剂处理区间与该运输空间中有一温度落差,该交换空间可注入特定含量的液化态氮以控制温度,避免该干细胞制剂材料因该温度落差过大而产生非预期的影响,其中,于该交换空间中可控制温度控制、光照控制或灭菌度控制,在此不限定。该环境控制装置维持该运输单元中运输空间的一运输环境,该运输环境需保持一温度控制、一湿度控制、光照控制或灭菌度控制,使该干细胞制剂材料于运送途中可保持其活性、稳定度或避免裂解。When the present invention is working: when the operator arrives at the job, the identification card allows the operator to open the system to authorize the processing equipment to use stem cell preparations (unauthorized ones cannot be turned on); the Internet of Things terminal installed on the stem cell preparation production equipment displays The screen prompts safety production precautions, operating procedures, automatically receives task instructions, and automatically calls the operation instructions corresponding to the process; then the terminal device prompts for "pre-operation verification" in multimedia, including environmental safety and health requirements and quality management requirements. , after item-by-item confirmation before proceeding to the next step; there is an exchange space between the stem cell preparation processing section and the transportation space, and this exchange space serves as an environmental buffer between the stem cell preparation treatment section and the transportation space, preventing the stem cell preparation materials from being lost during transportation. If there is an excessive environmental difference, for example, there is a temperature drop between the stem cell preparation processing section and the transport space, the exchange space can be injected with a specific content of liquefied nitrogen to control the temperature, so as to prevent the stem cell preparation material from being damaged due to the large temperature drop. Unintended effects are produced, wherein temperature control, light control or sterilization degree control can be controlled in the exchange space, which is not limited here. The environment control device maintains a transportation environment in the transportation space of the transportation unit, and the transportation environment needs to maintain a temperature control, a humidity control, a light control or a sterilization degree control, so that the stem cell preparation material can maintain its activity during transportation, stability or avoid lysis.
以上所述仅为本发明的较佳实施例而已,并不用以限制本发明,凡在本发明的精神和原则之内所作的任何修改、等同替换和改进等,均应包含在本发明的保护范围之内。The above descriptions are only preferred embodiments of the present invention, and are not intended to limit the present invention. Any modifications, equivalent replacements and improvements made within the spirit and principles of the present invention should be included in the protection of the present invention. within range.
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