ES2153808T1 - TEST STRIP WITH IMPROVED ELECTROCHEMICAL BIOSENSOR. - Google Patents

TEST STRIP WITH IMPROVED ELECTROCHEMICAL BIOSENSOR.

Info

Publication number
ES2153808T1
ES2153808T1 ES98960645T ES98960645T ES2153808T1 ES 2153808 T1 ES2153808 T1 ES 2153808T1 ES 98960645 T ES98960645 T ES 98960645T ES 98960645 T ES98960645 T ES 98960645T ES 2153808 T1 ES2153808 T1 ES 2153808T1
Authority
ES
Spain
Prior art keywords
insulating substrate
indentation
conductive tracks
roof
test strip
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
ES98960645T
Other languages
Spanish (es)
Other versions
ES2153808T3 (en
Inventor
William F Crismore
Nigel A Surridge
Daniel R Mcminn
Eric R Diebold
Richard J Bodensteiner
R Dale Delk
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Roche Diagnostics Corp
Original Assignee
Roche Diagnostics Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roche Diagnostics Corp filed Critical Roche Diagnostics Corp
Publication of ES2153808T1 publication Critical patent/ES2153808T1/en
Application granted granted Critical
Publication of ES2153808T3 publication Critical patent/ES2153808T3/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/001—Enzyme electrodes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/28—Electrolytic cell components
    • G01N27/30—Electrodes, e.g. test electrodes; Half-cells
    • G01N27/327—Biochemical electrodes, e.g. electrical or mechanical details for in vitro measurements
    • G01N27/3271—Amperometric enzyme electrodes for analytes in body fluids, e.g. glucose in blood
    • G01N27/3272—Test elements therefor, i.e. disposable laminated substrates with electrodes, reagent and channels
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366—Apparatus specially adapted for solid-phase testing
    • G01N33/54373—Apparatus specially adapted for solid-phase testing involving physiochemical end-point determination, e.g. wave-guides, FETS, gratings
    • G01N33/5438—Electrodes
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/817—Enzyme or microbe electrode

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Urology & Nephrology (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Pathology (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Cell Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Electrochemistry (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Investigating Or Analyzing Materials By The Use Of Electric Means (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Treatments Of Macromolecular Shaped Articles (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
  • Polishing Bodies And Polishing Tools (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

Una tira de ensayo, que comprende: un primer sustrato aislante que tiene una primera y una segunda superficies, una indentación a lo largo de un borde y un orificio de ventilación; al menos dos pistas eléctricamente conductoras fijadas a la primera superficie del primer sustrato aislante; un segundo sustrato aislante que tiene una primera y una segunda superficies, una indentación similar a la indentación del primer sustrato aislante, y una primera y una segunda aberturas, estando la segunda superficie fijada a las pistas conductoras y a la primera superficie del primer sustrato aislante, y orientada de modo que la indentación del segundo sustrato aislante se encuentre sobre la indentación del primer sustrato aislante, dejando la primera abertura al descubierto parte de las pistas conductoras para conexión eléctrica a un medidor capaz de medir una propiedad eléctrica, dejando al descubierto la segunda abertura una parte diferente de las pistas conductoras y el orificio de ventilación; un reactivo de ensayo que se encuentra sobre, al menos, parte de las pistas conductoras dejadas al descubierto por la segunda abertura; y un techo que tiene superficies primera y segunda y una indentación que es similar a las indentaciones del primero y del segundo sustratos aislantes, estando fijada la segunda superficie del techo a la primera superficie del segundo sustrato aislante y posicionada de manera que 1) la segunda superficie del techo y la superficie del primer sustrato aislante formen paredes opuestas de una cámara de llenado por apilaridad, y 2) la indentación del techo se encuentre sobre las indentaciones del primero y del segundo sustratos aislantes.A test strip, comprising: a first insulating substrate having a first and a second surface, an indentation along an edge and a ventilation hole; at least two electrically conductive tracks fixed to the first surface of the first insulating substrate; a second insulating substrate having a first and second surfaces, an indentation similar to the indentation of the first insulating substrate, and a first and second openings, the second surface being fixed to the conductive tracks and the first surface of the first insulating substrate, and oriented so that the indentation of the second insulating substrate is on the indentation of the first insulating substrate, leaving the first opening exposed part of the conductive tracks for electrical connection to a meter capable of measuring an electrical property, exposing the second opening a different part of the conductive tracks and the vent hole; a test reagent that is located on at least part of the conductive tracks exposed by the second opening; and a roof having first and second surfaces and an indentation that is similar to the indentations of the first and second insulating substrates, the second roof surface being fixed to the first surface of the second insulating substrate and positioned so that 1) the second roof surface and the surface of the first insulating substrate form opposite walls of a stack-filling chamber, and 2) the roof indentation is on the indentations of the first and second insulating substrates.

ES98960645T 1997-12-05 1998-12-02 TEST STRIP WITH IMPROVED ELECTROCHEMICAL BIOSENSOR. Expired - Lifetime ES2153808T3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US985840 1997-12-05
US08/985,840 US5997817A (en) 1997-12-05 1997-12-05 Electrochemical biosensor test strip

Publications (2)

Publication Number Publication Date
ES2153808T1 true ES2153808T1 (en) 2001-03-16
ES2153808T3 ES2153808T3 (en) 2008-07-01

Family

ID=25531850

Family Applications (1)

Application Number Title Priority Date Filing Date
ES98960645T Expired - Lifetime ES2153808T3 (en) 1997-12-05 1998-12-02 TEST STRIP WITH IMPROVED ELECTROCHEMICAL BIOSENSOR.

Country Status (14)

Country Link
US (8) US5997817A (en)
EP (3) EP1577668B1 (en)
JP (7) JP3342477B2 (en)
CN (4) CN100538352C (en)
AR (2) AR017788A1 (en)
AU (1) AU732761B2 (en)
BR (2) BRPI9815122B8 (en)
CA (3) CA2481193C (en)
DE (3) DE1036320T1 (en)
ES (1) ES2153808T3 (en)
NO (1) NO328686B1 (en)
NZ (1) NZ504527A (en)
TW (3) TWI294521B (en)
WO (1) WO1999030152A1 (en)

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