GR930100040A - Improved oxidative coupling dye for spectrophotometric quantitative analysis of analytes. - Google Patents

Improved oxidative coupling dye for spectrophotometric quantitative analysis of analytes.

Info

Publication number
GR930100040A
GR930100040A GR930100040A GR930100040A GR930100040A GR 930100040 A GR930100040 A GR 930100040A GR 930100040 A GR930100040 A GR 930100040A GR 930100040 A GR930100040 A GR 930100040A GR 930100040 A GR930100040 A GR 930100040A
Authority
GR
Greece
Prior art keywords
dye
mtbh
ans
produce
oxidizing agent
Prior art date
Application number
GR930100040A
Other languages
Greek (el)
Other versions
GR1002975B (en
Inventor
S Yu Yeung
Original Assignee
Lifescan Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lifescan Inc filed Critical Lifescan Inc
Publication of GR930100040A publication Critical patent/GR930100040A/en
Publication of GR1002975B publication Critical patent/GR1002975B/en

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/26—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase
    • C12Q1/28—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase involving peroxidase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/26—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/54—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving glucose or galactose
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2326/00—Chromogens for determinations of oxidoreductase enzymes
    • C12Q2326/32—3-Methyl-2-benzothiazolinone hydrazone hydrochloride hydrate, i.e. MBTH
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/81—Packaged device or kit

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Analytical Chemistry (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Emergency Medicine (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Investigating Or Analyzing Non-Biological Materials By The Use Of Chemical Means (AREA)

Abstract

Μία συνεζευγμένη χρωστική, περιέχει 3-μεθυλ-2-βενζοθειαζολινονο υδραζόνη (ΜΤΒΗ) και 8-ανιλινο-1-ναφθαλινοσουλφονική ένωση (ANS), χρησιμοποιείται ως δείκτης σε μίασειρά αντιδράσεων που παράγουν ένα ισχυρό οξειδωτικόπαράγοντα όπως υπεροξείδιο του υδρογόνου ή άλλα υπεροξείδια ήυπερβορικές ενώσεις. Ο ισχυρός οξειδωτικός παράγων αντιδρά μετην συζυγική χρωστική δια να παραγάγει μία μπλέ χρωστικήένωση. Η συζυγιακή χρωστική ΜΤΒΗ-ANS παρουσιάζει ισχυρά καιεπίπεδο φασματική απορρόφηση στην περιοχή περίπου 600 έως 650νανομέτρα. Την περιοχή αυτή δεν την επηρεάζουν οι χρωστικέςτου αίματος και έτσι καθίσταται δυνατή μία μέτρηση τηςγλυκόζης και άλλων αναλυτών που αντιδρούν με το ένζυμοοξειδάσης προς παραγωγή του ισχυρού οξειδωτικού παράγοντοςδια χρησιμοποιήσεως οπτικών LTD επακριβώς άνευ πολλής οπτικήςκλιμακώσεως. Περαιτέρω τα ΜΤΒΗ και ANS είναι πολύ διαλυτά ειςτο υδατικό διάλυμα, αλλά καθίστανται αδιάλυτα μετά τηνοξειδωτική σύζευξη. Η μικρα διαλυτότης περιορίζει στοελάχιστον την εξασθένιση της χρωστικής και έτσι δίδει ένασταθερό τελικό σημείο.ωA conjugate dye, containing 3-methyl-2-benzothiazolinone hydrazone (MTBH) and 8-anilino-1-naphthalenesulfonate (ANS), is used as an indicator in a series of reactions that produce a strong oxidizing agent such as hydrogen peroxide or other peroxides or hyperboric compounds. The strong oxidizing agent reacts with the conjugate dye to produce a blue dye compound. The MTBH-ANS conjugate dye exhibits strong and flat spectral absorption in the region of approximately 600 to 650 nanometers. This region is not affected by blood pigments and thus it becomes possible to measure glucose and other analytes that react with the enzyme oxidase to produce the strong oxidizing agent using LTD optics precisely without much optical scaling. Furthermore, MTBH and ANS are very soluble in aqueous solution, but become insoluble after oxidative coupling. Low solubility minimizes dye attenuation and thus gives a stable end point.

GR930100040A 1992-02-03 1993-02-04 Improved oxidative coupling dye for spectrophotometric quantitative analysis of analytes. GR1002975B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US82965492A 1992-02-03 1992-02-03

Publications (2)

Publication Number Publication Date
GR930100040A true GR930100040A (en) 1993-10-29
GR1002975B GR1002975B (en) 1998-09-23

Family

ID=25255147

Family Applications (1)

Application Number Title Priority Date Filing Date
GR930100040A GR1002975B (en) 1992-02-03 1993-02-04 Improved oxidative coupling dye for spectrophotometric quantitative analysis of analytes.

Country Status (10)

Country Link
US (1) US5453360A (en)
EP (1) EP0555045B1 (en)
JP (1) JP3342077B2 (en)
AT (1) ATE159052T1 (en)
AU (1) AU659525B2 (en)
CA (1) CA2088652C (en)
DE (1) DE69314363T2 (en)
DK (1) DK0555045T3 (en)
ES (1) ES2109429T3 (en)
GR (1) GR1002975B (en)

Families Citing this family (117)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4935346A (en) 1986-08-13 1990-06-19 Lifescan, Inc. Minimum procedure system for the determination of analytes
US5710012A (en) * 1993-08-25 1998-01-20 Actimed Laboratories, Inc. Salt of 6-carboxy-3-methylbenzothiazolone hydrazone hydrate in colorimetric determination of hydrogen peroxide
US5582184A (en) * 1993-10-13 1996-12-10 Integ Incorporated Interstitial fluid collection and constituent measurement
US5563031A (en) * 1994-09-08 1996-10-08 Lifescan, Inc. Highly stable oxidative coupling dye for spectrophotometric determination of analytes
US5922530A (en) 1994-09-08 1999-07-13 Lifescan, Inc. Stable coupling dye for photometric determination of analytes
US5719034A (en) * 1995-03-27 1998-02-17 Lifescan, Inc. Chemical timer for a visual test strip
EP0840798A1 (en) * 1995-05-25 1998-05-13 Actimed Laboratories, Inc. Use of a salt of 6-carboxy-3-methylbenzothiazolone hydrazone hydrate in colorimetric determination of hydrogen peroxide
US5879367A (en) * 1995-09-08 1999-03-09 Integ, Inc. Enhanced interstitial fluid collection
US5753452A (en) * 1996-04-04 1998-05-19 Lifescan, Inc. Reagent test strip for blood glucose determination
IL120587A (en) * 1996-04-04 2000-10-31 Lifescan Inc Reagent test strip for determination of blood glucose
US5989845A (en) 1996-04-05 1999-11-23 Mercury Diagnostics, Inc. Diagnostic compositions and devices utilizing same
US5776719A (en) * 1997-07-07 1998-07-07 Mercury Diagnostics, Inc. Diagnostic compositions and devices utilizing same
US6040151A (en) * 1998-03-10 2000-03-21 Mercury Diagnostics, Inc. Diagnostic compositions and devices utilizing same
US5962215A (en) 1996-04-05 1999-10-05 Mercury Diagnostics, Inc. Methods for testing the concentration of an analyte in a body fluid
EP2290362B1 (en) 1996-10-30 2013-01-23 F. Hoffmann-La Roche AG Synchronized analyte testing system
US5885839A (en) * 1997-04-15 1999-03-23 Lxn Corporation Methods of determining initiation and variable end points for measuring a chemical reaction
US6121050A (en) * 1997-08-29 2000-09-19 Han; Chi-Neng Arthur Analyte detection systems
WO1999017117A1 (en) * 1997-09-30 1999-04-08 Amira Medical Analytical device with capillary reagent carrier
US7407811B2 (en) 1997-12-22 2008-08-05 Roche Diagnostics Operations, Inc. System and method for analyte measurement using AC excitation
US7494816B2 (en) 1997-12-22 2009-02-24 Roche Diagnostic Operations, Inc. System and method for determining a temperature during analyte measurement
US7390667B2 (en) 1997-12-22 2008-06-24 Roche Diagnostics Operations, Inc. System and method for analyte measurement using AC phase angle measurements
US8071384B2 (en) 1997-12-22 2011-12-06 Roche Diagnostics Operations, Inc. Control and calibration solutions and methods for their use
US6391005B1 (en) 1998-03-30 2002-05-21 Agilent Technologies, Inc. Apparatus and method for penetration with shaft having a sensor for sensing penetration depth
JP2002523195A (en) 1998-08-31 2002-07-30 ジョンソン・アンド・ジョンソン・コンシューマー・カンパニーズ・インコーポレイテッド Electronic transport device with blade
US6368563B1 (en) * 1999-03-12 2002-04-09 Integ, Inc. Collection well for body fluid tester
ATE290902T1 (en) 1999-04-16 2005-04-15 Johnson & Johnson Consumer DEVICE FOR IONTOPHORETIC ADMINISTRATION OF MEDICATION WITH INTERNAL SENSORS
US6218571B1 (en) * 1999-10-27 2001-04-17 Lifescan, Inc. 8-(anilino)-1-naphthalenesulfonate analogs
US6458326B1 (en) 1999-11-24 2002-10-01 Home Diagnostics, Inc. Protective test strip platform
US6743597B1 (en) 2000-06-13 2004-06-01 Lifescan, Inc. Compositions containing a urea derivative dye for detecting an analyte and methods for using the same
KR20020000933A (en) * 2000-06-22 2002-01-09 손동준 A preparation method of test strip for measuring glucose content in whole blood
US8641644B2 (en) 2000-11-21 2014-02-04 Sanofi-Aventis Deutschland Gmbh Blood testing apparatus having a rotatable cartridge with multiple lancing elements and testing means
US6562625B2 (en) 2001-02-28 2003-05-13 Home Diagnostics, Inc. Distinguishing test types through spectral analysis
US6541266B2 (en) 2001-02-28 2003-04-01 Home Diagnostics, Inc. Method for determining concentration of an analyte in a test strip
US6525330B2 (en) 2001-02-28 2003-02-25 Home Diagnostics, Inc. Method of strip insertion detection
US9226699B2 (en) 2002-04-19 2016-01-05 Sanofi-Aventis Deutschland Gmbh Body fluid sampling module with a continuous compression tissue interface surface
US7041068B2 (en) 2001-06-12 2006-05-09 Pelikan Technologies, Inc. Sampling module device and method
US7344507B2 (en) 2002-04-19 2008-03-18 Pelikan Technologies, Inc. Method and apparatus for lancet actuation
US8337419B2 (en) 2002-04-19 2012-12-25 Sanofi-Aventis Deutschland Gmbh Tissue penetration device
US9427532B2 (en) 2001-06-12 2016-08-30 Sanofi-Aventis Deutschland Gmbh Tissue penetration device
US7981056B2 (en) 2002-04-19 2011-07-19 Pelikan Technologies, Inc. Methods and apparatus for lancet actuation
US7033371B2 (en) 2001-06-12 2006-04-25 Pelikan Technologies, Inc. Electric lancet actuator
WO2002100254A2 (en) 2001-06-12 2002-12-19 Pelikan Technologies, Inc. Method and apparatus for lancet launching device integrated onto a blood-sampling cartridge
CA2448902C (en) 2001-06-12 2010-09-07 Pelikan Technologies, Inc. Self optimizing lancing device with adaptation means to temporal variations in cutaneous properties
US9795747B2 (en) 2010-06-02 2017-10-24 Sanofi-Aventis Deutschland Gmbh Methods and apparatus for lancet actuation
US6844149B2 (en) 2001-06-29 2005-01-18 International Business Machines Corporation Method, system, and apparatus for measurement and recording of blood chemistry and other physiological measurements
US20030077205A1 (en) * 2001-10-24 2003-04-24 Xu Tom C. Diagnostic test optical fiber tips
US7547287B2 (en) 2002-04-19 2009-06-16 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7229458B2 (en) 2002-04-19 2007-06-12 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US8579831B2 (en) 2002-04-19 2013-11-12 Sanofi-Aventis Deutschland Gmbh Method and apparatus for penetrating tissue
US9314194B2 (en) 2002-04-19 2016-04-19 Sanofi-Aventis Deutschland Gmbh Tissue penetration device
US8360992B2 (en) 2002-04-19 2013-01-29 Sanofi-Aventis Deutschland Gmbh Method and apparatus for penetrating tissue
US9795334B2 (en) 2002-04-19 2017-10-24 Sanofi-Aventis Deutschland Gmbh Method and apparatus for penetrating tissue
US7901362B2 (en) 2002-04-19 2011-03-08 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US9248267B2 (en) 2002-04-19 2016-02-02 Sanofi-Aventis Deustchland Gmbh Tissue penetration device
US7674232B2 (en) 2002-04-19 2010-03-09 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US8784335B2 (en) 2002-04-19 2014-07-22 Sanofi-Aventis Deutschland Gmbh Body fluid sampling device with a capacitive sensor
US8702624B2 (en) 2006-09-29 2014-04-22 Sanofi-Aventis Deutschland Gmbh Analyte measurement device with a single shot actuator
US7491178B2 (en) 2002-04-19 2009-02-17 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US8221334B2 (en) 2002-04-19 2012-07-17 Sanofi-Aventis Deutschland Gmbh Method and apparatus for penetrating tissue
US8267870B2 (en) 2002-04-19 2012-09-18 Sanofi-Aventis Deutschland Gmbh Method and apparatus for body fluid sampling with hybrid actuation
US7297122B2 (en) 2002-04-19 2007-11-20 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7232451B2 (en) 2002-04-19 2007-06-19 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7892185B2 (en) 2002-04-19 2011-02-22 Pelikan Technologies, Inc. Method and apparatus for body fluid sampling and analyte sensing
US7976476B2 (en) 2002-04-19 2011-07-12 Pelikan Technologies, Inc. Device and method for variable speed lancet
US7226461B2 (en) 2002-04-19 2007-06-05 Pelikan Technologies, Inc. Method and apparatus for a multi-use body fluid sampling device with sterility barrier release
US7892183B2 (en) 2002-04-19 2011-02-22 Pelikan Technologies, Inc. Method and apparatus for body fluid sampling and analyte sensing
US7909778B2 (en) 2002-04-19 2011-03-22 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7331931B2 (en) 2002-04-19 2008-02-19 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US8574895B2 (en) 2002-12-30 2013-11-05 Sanofi-Aventis Deutschland Gmbh Method and apparatus using optical techniques to measure analyte levels
ES2347248T3 (en) 2003-05-30 2010-10-27 Pelikan Technologies Inc. PROCEDURE AND APPLIANCE FOR FLUID INJECTION.
EP1633235B1 (en) 2003-06-06 2014-05-21 Sanofi-Aventis Deutschland GmbH Apparatus for body fluid sampling and analyte sensing
WO2006001797A1 (en) 2004-06-14 2006-01-05 Pelikan Technologies, Inc. Low pain penetrating
US8058077B2 (en) 2003-06-20 2011-11-15 Roche Diagnostics Operations, Inc. Method for coding information on a biosensor test strip
US8148164B2 (en) 2003-06-20 2012-04-03 Roche Diagnostics Operations, Inc. System and method for determining the concentration of an analyte in a sample fluid
US7452457B2 (en) 2003-06-20 2008-11-18 Roche Diagnostics Operations, Inc. System and method for analyte measurement using dose sufficiency electrodes
US7488601B2 (en) 2003-06-20 2009-02-10 Roche Diagnostic Operations, Inc. System and method for determining an abused sensor during analyte measurement
US7597793B2 (en) 2003-06-20 2009-10-06 Roche Operations Ltd. System and method for analyte measurement employing maximum dosing time delay
US7645421B2 (en) 2003-06-20 2010-01-12 Roche Diagnostics Operations, Inc. System and method for coding information on a biosensor test strip
US7645373B2 (en) 2003-06-20 2010-01-12 Roche Diagnostic Operations, Inc. System and method for coding information on a biosensor test strip
US8206565B2 (en) 2003-06-20 2012-06-26 Roche Diagnostics Operation, Inc. System and method for coding information on a biosensor test strip
US7718439B2 (en) 2003-06-20 2010-05-18 Roche Diagnostics Operations, Inc. System and method for coding information on a biosensor test strip
US7604721B2 (en) 2003-06-20 2009-10-20 Roche Diagnostics Operations, Inc. System and method for coding information on a biosensor test strip
US7220034B2 (en) * 2003-07-11 2007-05-22 Rudolph Technologies, Inc. Fiber optic darkfield ring light
US8282576B2 (en) 2003-09-29 2012-10-09 Sanofi-Aventis Deutschland Gmbh Method and apparatus for an improved sample capture device
WO2005037095A1 (en) 2003-10-14 2005-04-28 Pelikan Technologies, Inc. Method and apparatus for a variable user interface
US7822454B1 (en) 2005-01-03 2010-10-26 Pelikan Technologies, Inc. Fluid sampling device with improved analyte detecting member configuration
EP1706026B1 (en) 2003-12-31 2017-03-01 Sanofi-Aventis Deutschland GmbH Method and apparatus for improving fluidic flow and sample capture
RU2006132051A (en) 2004-02-06 2008-03-20 БАЙЕР ХЕЛТКЭР ЭлЭлСи (US) OXIDIZABLE COMPOUNDS AS AN INTERNAL STANDARD FOR BIOSENSORS AND METHOD OF APPLICATION
EP1751546A2 (en) 2004-05-20 2007-02-14 Albatros Technologies GmbH & Co. KG Printable hydrogel for biosensors
WO2005120365A1 (en) 2004-06-03 2005-12-22 Pelikan Technologies, Inc. Method and apparatus for a fluid sampling device
US9775553B2 (en) 2004-06-03 2017-10-03 Sanofi-Aventis Deutschland Gmbh Method and apparatus for a fluid sampling device
US7569126B2 (en) 2004-06-18 2009-08-04 Roche Diagnostics Operations, Inc. System and method for quality assurance of a biosensor test strip
US7556723B2 (en) 2004-06-18 2009-07-07 Roche Diagnostics Operations, Inc. Electrode design for biosensor
US20060002817A1 (en) * 2004-06-30 2006-01-05 Sebastian Bohm Flow modulation devices
US8343074B2 (en) 2004-06-30 2013-01-01 Lifescan Scotland Limited Fluid handling devices
BRPI0518638A2 (en) 2004-12-13 2008-12-02 Bayer Healthcare Llc Method of differentiating blood from control solutions containing a common analyte
US8652831B2 (en) 2004-12-30 2014-02-18 Sanofi-Aventis Deutschland Gmbh Method and apparatus for analyte measurement test time
CN103558284B (en) 2005-07-20 2017-04-12 安晟信医疗科技控股公司 Gated amperometry
CA2986870A1 (en) 2005-09-30 2007-04-12 Ascensia Diabetes Care Holdings Ag Gated voltammetry
US20070243578A1 (en) * 2006-04-18 2007-10-18 Ken Mullen Method, system, apparatus and kit for semen analysis
US20080057528A1 (en) * 2006-08-30 2008-03-06 Kimberly-Clark Worldwide, Inc. Detection of hydrogen peroxide released by enzyme-catalyzed oxidation of an analyte
US20080100689A1 (en) * 2006-10-31 2008-05-01 Selwayan Saini Method for manufacturing an analytical test strip with an electroluminescent component
US7740801B2 (en) * 2006-10-31 2010-06-22 Lifescan Scotland Limited System for determination of an analyte in a bodily fluid sample that includes an electroluminescent component
US20080101986A1 (en) * 2006-10-31 2008-05-01 Selwayan Saini Analytical test strip with electroluminescent module
CA2608924A1 (en) 2006-10-31 2008-04-30 Lifescan Scotland Limited Analytical test strip with electroluminescent module
JP2008116453A (en) 2006-10-31 2008-05-22 Lifescan Scotland Ltd Analytical test strip with electroluminescent lamp
US20080101984A1 (en) * 2006-10-31 2008-05-01 Selwayan Saini Method for determining an analyte in a bodily fluid sample
US8012761B2 (en) * 2006-12-14 2011-09-06 Kimberly-Clark Worldwide, Inc. Detection of formaldehyde in urine samples
KR101523754B1 (en) * 2007-03-05 2015-05-28 어드밴스드 리퀴드 로직, 아이엔씨. Analytical evaluation method based on hydrogen peroxide droplet
WO2009076302A1 (en) 2007-12-10 2009-06-18 Bayer Healthcare Llc Control markers for auto-detection of control solution and methods of use
WO2009126900A1 (en) 2008-04-11 2009-10-15 Pelikan Technologies, Inc. Method and apparatus for analyte detecting device
US9375169B2 (en) 2009-01-30 2016-06-28 Sanofi-Aventis Deutschland Gmbh Cam drive for managing disposable penetrating member actions with a single motor and motor and control system
US8501111B2 (en) 2009-05-21 2013-08-06 Tom Cheng Xu Small volume and fast acting optical analyte sensor
US8965476B2 (en) 2010-04-16 2015-02-24 Sanofi-Aventis Deutschland Gmbh Tissue penetration device
CN102305852B (en) * 2011-05-17 2014-12-10 湖州麦迪诺华医疗科技有限公司 Coloring agent for in vitro diagnostic device
EP3172570A4 (en) 2014-07-25 2017-12-27 Becton, Dickinson and Company Analyte test strip assays, and test strips and kits for use in practicing the same
CN113767276B (en) * 2019-04-26 2024-10-18 舒万诺知识产权公司 Chemical hydrogen peroxide indicator

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4089747A (en) * 1976-08-09 1978-05-16 Eastman Kodak Company Compositions for the detection of hydrogen peroxide
US4119405A (en) * 1978-02-13 1978-10-10 Miles Laboratories, Inc. Test means and method for interference resistant determination of oxidizing substances
US4444789A (en) * 1980-05-30 1984-04-24 University Of Georgia Research Foundation, Inc. Use of 8-anilino-1-naphthalenesulfonate as a vaginal contraceptive
JPS5856699A (en) * 1981-09-25 1983-04-04 Maruho Kk Quick determination of guanase
US5049487A (en) * 1986-08-13 1991-09-17 Lifescan, Inc. Automated initiation of timing of reflectance readings
US5059394A (en) * 1986-08-13 1991-10-22 Lifescan, Inc. Analytical device for the automated determination of analytes in fluids
US4935346A (en) * 1986-08-13 1990-06-19 Lifescan, Inc. Minimum procedure system for the determination of analytes
DE8710758U1 (en) * 1987-08-06 1987-10-15 Mollificio Fede di Dell'Oro P.I. Mario, Taceno, Como Flexible keyring
US5215890A (en) * 1988-11-03 1993-06-01 Spyros Theodoropulos Chromogenic substrate to peroxidase enzymes
WO1990006372A1 (en) * 1988-12-01 1990-06-14 Microprobe Corporation Substrates for peroxidase assaying
US5332662A (en) * 1992-07-31 1994-07-26 Syntex (U.S.A.) Inc. Methods for determining peroxidatively active substances

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CA2088652A1 (en) 1993-08-04
DE69314363D1 (en) 1997-11-13
CA2088652C (en) 2008-07-29
DK0555045T3 (en) 1998-03-16
JPH0611447A (en) 1994-01-21
ATE159052T1 (en) 1997-10-15
EP0555045B1 (en) 1997-10-08
GR1002975B (en) 1998-09-23
AU659525B2 (en) 1995-05-18
ES2109429T3 (en) 1998-01-16
EP0555045A1 (en) 1993-08-11
US5453360A (en) 1995-09-26
AU3219193A (en) 1993-08-05
JP3342077B2 (en) 2002-11-05
DE69314363T2 (en) 1998-02-19

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