JP6750294B2 - Pulse wave detection device and biological information measurement device - Google Patents

Pulse wave detection device and biological information measurement device Download PDF

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JP6750294B2
JP6750294B2 JP2016091665A JP2016091665A JP6750294B2 JP 6750294 B2 JP6750294 B2 JP 6750294B2 JP 2016091665 A JP2016091665 A JP 2016091665A JP 2016091665 A JP2016091665 A JP 2016091665A JP 6750294 B2 JP6750294 B2 JP 6750294B2
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pressure
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JP2017196309A5 (en
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雄樹 加藤
雄樹 加藤
純平 間野
純平 間野
麗二 藤田
麗二 藤田
新吾 山下
新吾 山下
小椋 敏彦
敏彦 小椋
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Omron Healthcare Co Ltd
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Priority to EP17789378.1A priority patent/EP3453320B1/en
Priority to PCT/JP2017/015752 priority patent/WO2017188093A1/en
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/02Detecting, measuring or recording for evaluating the cardiovascular system, e.g. pulse, heart rate, blood pressure or blood flow
    • A61B5/021Measuring pressure in heart or blood vessels
    • A61B5/022Measuring pressure in heart or blood vessels by applying pressure to close blood vessels, e.g. against the skin; Ophthalmodynamometers
    • A61B5/0225Measuring pressure in heart or blood vessels by applying pressure to close blood vessels, e.g. against the skin; Ophthalmodynamometers the pressure being controlled by electric signals, e.g. derived from Korotkoff sounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/02Detecting, measuring or recording for evaluating the cardiovascular system, e.g. pulse, heart rate, blood pressure or blood flow
    • A61B5/021Measuring pressure in heart or blood vessels
    • A61B5/02108Measuring pressure in heart or blood vessels from analysis of pulse wave characteristics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/02Detecting, measuring or recording for evaluating the cardiovascular system, e.g. pulse, heart rate, blood pressure or blood flow
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/68Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
    • A61B5/6801Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be attached to or worn on the body surface
    • A61B5/6843Monitoring or controlling sensor contact pressure
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B2562/00Details of sensors; Constructional details of sensor housings or probes; Accessories for sensors
    • A61B2562/02Details of sensors specially adapted for in-vivo measurements
    • A61B2562/0247Pressure sensors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B2562/00Details of sensors; Constructional details of sensor housings or probes; Accessories for sensors
    • A61B2562/04Arrangements of multiple sensors of the same type
    • A61B2562/043Arrangements of multiple sensors of the same type in a linear array
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B2562/00Details of sensors; Constructional details of sensor housings or probes; Accessories for sensors
    • A61B2562/16Details of sensor housings or probes; Details of structural supports for sensors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B2562/00Details of sensors; Constructional details of sensor housings or probes; Accessories for sensors
    • A61B2562/22Arrangements of medical sensors with cables or leads; Connectors or couplings specifically adapted for medical sensors
    • A61B2562/225Connectors or couplings
    • A61B2562/227Sensors with electrical connectors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/68Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
    • A61B5/6801Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be attached to or worn on the body surface
    • A61B5/6813Specially adapted to be attached to a specific body part
    • A61B5/6824Arm or wrist

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Cardiology (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
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  • Measuring Pulse, Heart Rate, Blood Pressure Or Blood Flow (AREA)

Description

本発明は、圧脈波センサ、脈波検出装置、及び、生体情報測定装置に関する。 The present invention relates to a pressure pulse wave sensor, a pulse wave detection device, and a biological information measurement device.

手首の橈骨動脈等の動脈が通る生体部位に圧力センサを直接接触させた状態で、この圧力センサにより検出される情報を用いて脈拍又は血圧等の生体情報を測定することのできる生体情報測定装置が知られている(例えば特許文献1参照)。 A biological information measuring device capable of measuring biological information such as pulse or blood pressure using information detected by the pressure sensor in a state where the pressure sensor is in direct contact with a living body part through which an artery such as a radial artery of the wrist passes. Is known (for example, refer to Patent Document 1).

特許文献1に記載の生体情報測定装置に搭載される圧力センサは、回路基板と、この回路基板上に設けられたスペーサと、このスペーサの上に設けられたセンサチップと、この回路基板を収容するケースと、回路基板を保護するための保護プレートと、を備える。この保護プレートには開口が設けられており、この開口からセンサチップが突出する構成となっている。 The pressure sensor mounted on the biological information measuring device described in Patent Document 1 accommodates a circuit board, a spacer provided on the circuit board, a sensor chip provided on the spacer, and the circuit board. And a protection plate for protecting the circuit board. An opening is provided in this protection plate, and the sensor chip is configured to project from this opening.

特開平4−67839号公報JP-A-4-67839

特許文献1に記載のセンサ部では、センサチップが保護プレートの開口から突出している。このため、圧力センサにおいて手首と接触する部分はセンサチップの表面が支配的となり、センサチップ表面に加わる力が大きくなる。したがって、例えば1日等の長い時間に渡って生体情報測定装置を装着することを想定した場合には、センサチップの耐久性向上が課題となる。 In the sensor unit described in Patent Document 1, the sensor chip projects from the opening of the protection plate. For this reason, the surface of the sensor chip is dominant in the portion of the pressure sensor that comes into contact with the wrist, and the force applied to the surface of the sensor chip becomes large. Therefore, when it is assumed that the biological information measuring device is attached for a long time such as one day, improvement of durability of the sensor chip becomes a problem.

本発明は、上記事情に鑑みてなされたものであり、長時間の装着を行う場合の耐久性を十分に確保することができかつ製造コストを抑えることができる圧脈波センサ、脈波検出装置、及び、生体情報測定装置を提供することを目的とする。 The present invention has been made in view of the above circumstances, and a pressure pulse wave sensor and a pulse wave detection device capable of sufficiently ensuring durability when wearing for a long time and suppressing manufacturing cost. And to provide a biological information measuring device.

本発明の脈波検出装置は、橈骨動脈と交差する一方向に並ぶ複数の圧力検出素子からなる素子列を有するセンサチップと、前記センサチップが固定される基板と、を含むセンサ部と、前記センサ部を保護する保護部材と、前記圧力検出素子が形成された前記センサチップの検出面と前記保護部材に設けられた開口部との間に充填されている充填と、を有し、前記開口部が、前記センサチップの前記基板に固定された側の反対側であって前記検出面に垂直な垂直方向において前記検出面と対向する位置に配置されている、圧脈波センサと、前記圧脈波センサを前記一方向及び前記垂直方向直交する方向の周りに回転させる回転機構と、を備え、前記保護部材の外周面は、前記開口部が形成された頂面と、前記頂面の前記一方向の両端縁と連続する面であって、前記開口部の開口面に対して傾斜した傾斜面と、を有し、前記傾斜面の傾斜角度は、前記回転機構によって前記圧脈波センサが回転可能な回転角の最大値未満になっているものである。 The pulse wave detection device of the present invention, a sensor section having a sensor chip having an element row composed of a plurality of pressure detection elements arranged in one direction intersecting the radial artery, and a substrate to which the sensor chip is fixed , a sensor unit, A protective member for protecting the sensor portion , and a filling material filled between a detection surface of the sensor chip on which the pressure detection element is formed and an opening provided in the protective member, and The pressure pulse wave sensor, wherein the opening is arranged at a position opposite to the side of the sensor chip fixed to the substrate and facing the detection surface in a vertical direction perpendicular to the detection surface, A rotation mechanism that rotates the pressure pulse wave sensor around the direction orthogonal to the one direction and the vertical direction , and the outer peripheral surface of the protection member has a top surface on which the opening is formed, and the top surface. A sloped surface that is continuous with both end edges in the one direction and that is sloped with respect to the opening surface of the opening, and the tilt angle of the tilted surface depends on the rotation mechanism. The rotation angle of the sensor is less than the maximum value.

本発明の生体情報測定装置は、前記脈波検出装置と、前記圧脈波センサによって検出された圧脈波に基づいて生体情報を算出する生体情報算出部と、を備えるものである。 The biological information measuring device of the present invention includes the pulse wave detecting device and a biological information calculating unit that calculates biological information based on the pressure pulse wave detected by the pressure pulse wave sensor.

本発明によれば、長時間の装着を行う場合の耐久性を十分に確保することができかつ製造コストを抑えることができる圧脈波センサとこれを備える生体情報測定装置を提供することができる。 Advantageous Effects of Invention According to the present invention, it is possible to provide a pressure pulse wave sensor capable of sufficiently ensuring durability when wearing for a long time and suppressing manufacturing costs, and a biological information measuring device including the pressure pulse wave sensor. ..

本発明の一実施形態である生体情報測定装置100の概略構成を示す模式図である。It is a schematic diagram which shows schematic structure of the biological information measuring device 100 which is one Embodiment of this invention. 図1に示す圧脈波センサ10の外観構成を示す分解斜視図である。FIG. 2 is an exploded perspective view showing an external configuration of a pressure pulse wave sensor 10 shown in FIG. 1. 図1に示す圧脈波センサ10の外観構成を示す斜視図である。It is a perspective view which shows the external appearance structure of the pressure pulse wave sensor 10 shown in FIG. 図2に示すセンサ部20の外観構成を示す模式図である。It is a schematic diagram which shows the external structure of the sensor part 20 shown in FIG. 図3に示すV−V線の断面模式図である。It is a cross-sectional schematic diagram of the VV line shown in FIG. 図3に示す圧脈波センサ10を方向Zから見た平面図である。4 is a plan view of the pressure pulse wave sensor 10 shown in FIG. 3 viewed from a direction Z. FIG. 図2に示す圧脈波センサ10の保護カバー40の変形例である保護カバー401の外観構成を示す斜視図である。FIG. 7 is a perspective view showing an external configuration of a protective cover 401 that is a modified example of the protective cover 40 of the pressure pulse wave sensor 10 shown in FIG. 2. 図2に示す圧脈波センサ10の変形例である圧脈波センサ12の断面模式図である。FIG. 9 is a schematic cross-sectional view of a pressure pulse wave sensor 12 which is a modified example of the pressure pulse wave sensor 10 shown in FIG. 2. 図2に示す圧脈波センサ10のセンサ部20の変形例であるセンサ部201の外観構成を示す斜視図である。FIG. 9 is a perspective view showing an external configuration of a sensor unit 201 which is a modified example of the sensor unit 20 of the pressure pulse wave sensor 10 shown in FIG. 2. 図2に示す圧脈波センサ10の変形例の断面模式図である。It is a cross-sectional schematic diagram of the modification of the pressure pulse wave sensor 10 shown in FIG.

以下、本発明の実施形態について図面を参照して説明する。 Hereinafter, embodiments of the present invention will be described with reference to the drawings.

図1は、本発明の一実施形態である生体情報測定装置100の概略構成を示す模式図である。 FIG. 1 is a schematic diagram showing a schematic configuration of a biological information measuring device 100 which is an embodiment of the present invention.

生体情報測定装置100は、筐体80と、筐体80によって支持されている空気袋70と、空気袋70に固定された回転駆動部60と、回転駆動部60によって回転自在に支持された圧脈波センサ10と、を備える。生体情報測定装置100は、図示しないバンドによって被測定者の手首に装着して用いられる。 The biological information measuring device 100 includes a housing 80, an air bag 70 supported by the housing 80, a rotation drive unit 60 fixed to the air bag 70, and a pressure rotatably supported by the rotation drive unit 60. The pulse wave sensor 10 is provided. The biological information measuring device 100 is used by being worn on the wrist of the person to be measured with a band (not shown).

空気袋70は、回転駆動部60及び圧脈波センサ10を手首の体表面に対して押圧する押圧部材を構成する。空気袋70は、筐体80に内蔵されている図示しないポンプによって内圧が調整される。ポンプは、筐体80に内蔵されている制御部によって制御される。 The air bag 70 constitutes a pressing member that presses the rotation drive unit 60 and the pressure pulse wave sensor 10 against the body surface of the wrist. The inner pressure of the air bladder 70 is adjusted by a pump (not shown) built in the housing 80. The pump is controlled by a control unit built in the housing 80.

回転駆動部60は、圧脈波センサ10の後述する検出面に沿う互いに直交する2つの方向の各々に伸びる軸の周りに圧脈波センサ10を回転させるための回転機構61と、回転機構61を駆動するアクチュエータ62と、を有する。アクチュエータ62は、筐体80に内蔵されている制御部によって制御される。 The rotation drive unit 60 includes a rotation mechanism 61 for rotating the pressure pulse wave sensor 10 around axes extending in two directions orthogonal to each other along a detection surface of the pressure pulse wave sensor 10 described later, and a rotation mechanism 61. And an actuator 62 for driving the. The actuator 62 is controlled by the control unit built in the housing 80.

圧脈波センサ10は、空気袋70によって所定の押圧力で体表面に対して押圧されている状態で、手首の内部を通る橈骨動脈Tから体表面に伝わる圧力振動波である圧脈波を検出するセンサである。筐体80内には、圧脈波センサ10により検出された圧脈波に基づいて脈拍数、心拍数、又は、血圧値等の生体情報を算出する不図示の生体情報算出部が内蔵されている。 The pressure pulse wave sensor 10 generates a pressure pulse wave which is a pressure vibration wave transmitted from the radial artery T passing through the inside of the wrist to the body surface while being pressed against the body surface by the air bag 70 with a predetermined pressing force. It is a sensor for detecting. In the housing 80, a biological information calculation unit (not shown) that calculates biological information such as a pulse rate, a heart rate, or a blood pressure value based on the pressure pulse wave detected by the pressure pulse wave sensor 10 is built in. There is.

図2は、図1に示す圧脈波センサ10の外観構成を示す分解斜視図である。図3は、図1に示す圧脈波センサ10の外観構成を示す斜視図である。 FIG. 2 is an exploded perspective view showing an external configuration of the pressure pulse wave sensor 10 shown in FIG. FIG. 3 is a perspective view showing an external configuration of the pressure pulse wave sensor 10 shown in FIG.

圧脈波センサ10は、一方向である方向Xに沿って長手の形状の2つのセンサ部20と、2つのセンサ部20が方向Xに直交する方向Yに並べて固定されたフレキシブル基板21と、フレキシブル基板21が固定されたベース30と、フレキシブル基板21が固定されたベース30に固定されて2つのセンサ部20を保護する保護部材としての保護カバー40と、を備える。 The pressure pulse wave sensor 10 includes two sensor portions 20 each having a longitudinal shape along a direction X, which is one direction, and a flexible substrate 21 on which the two sensor portions 20 are arranged and fixed in a direction Y orthogonal to the direction X. A base 30 to which the flexible substrate 21 is fixed and a protective cover 40 as a protective member that is fixed to the base 30 to which the flexible substrate 21 is fixed and protects the two sensor units 20 are provided.

ベース30は、方向X及び方向Yに直交する方向Zから見た平面形状が矩形状であり、フレキシブル基板21が載置される載置面32を有する。載置面32には、方向Zに向かって載置面32を貫通するベース貫通孔33が、センサ部20の数に対応して2つ設けられている。また、載置面32において方向Yの両端位置には、フレキシブル基板21が挿通可能な大きさの開口34が設けられている。フレキシブル基板21の両端は、この開口34を通してベース30の裏側に引き出される。 The base 30 has a rectangular planar shape when viewed in the direction Z orthogonal to the direction X and the direction Y, and has a mounting surface 32 on which the flexible substrate 21 is mounted. The mounting surface 32 is provided with two base through holes 33 penetrating the mounting surface 32 in the direction Z in correspondence with the number of the sensor units 20. In addition, on the mounting surface 32, at both ends in the direction Y, openings 34 having a size through which the flexible substrate 21 can be inserted are provided. Both ends of the flexible substrate 21 are pulled out to the back side of the base 30 through the openings 34.

保護カバー40は、方向Zから見た平面形状がベース30の外形と同様の大きさの矩形状を呈しており、フレキシブル基板21がベース30に固定された状態で、ベース30の載置面32の周囲の面に固定される。 The protection cover 40 has a rectangular shape in a plan view when viewed in the direction Z and has a size similar to the outer shape of the base 30, and the mounting surface 32 of the base 30 in the state where the flexible substrate 21 is fixed to the base 30. It is fixed on the surface around.

保護カバー40は、ベース30に固定された状態で2つのセンサ部20の各々と対向する位置に形成された2つの開口部42を有する。保護カバー40の外周面(図3に示す状態で外部に露出する面)は、平坦な頂面41と、頂面41の端縁45と連続する傾斜面44と、傾斜面44の端縁と連続する頂面41に垂直な垂直面46と、を備える。保護カバー40の詳細形状については後述する。 The protective cover 40 has two openings 42 formed at positions facing the two sensor units 20 while being fixed to the base 30. The outer peripheral surface of the protective cover 40 (the surface exposed to the outside in the state shown in FIG. 3) has a flat top surface 41, an inclined surface 44 continuous with the edge 45 of the top surface 41, and an edge of the inclined surface 44. A vertical surface 46 perpendicular to the continuous top surface 41. The detailed shape of the protective cover 40 will be described later.

図4は、図2に示すセンサ部20の外観構成を示す模式図である。図5は、図3に示すV−V線の断面模式図である。 FIG. 4 is a schematic diagram showing an external configuration of the sensor unit 20 shown in FIG. FIG. 5 is a schematic cross-sectional view taken along the line VV shown in FIG.

センサ部20は、センサチップ22と、凹部51を有し凹部51の底面52にセンサチップ22が固定された容器状の基板50と、を備える。 The sensor unit 20 includes a sensor chip 22 and a container-shaped substrate 50 having a recess 51 and having the bottom surface 52 of the recess 51 fixed to the sensor chip 22.

センサチップ22は、シリコン単結晶又はガリウム−砒素等の化合物半導体の単結晶等の半導体基板23を備える。半導体基板23は、方向Xが長手方向となる矩形状となっている。半導体基板23の表面には、方向Xに沿って配列された複数の圧力検出素子24からなる素子列25が形成されている。圧力検出素子24は、素子に加わる歪みを圧力信号として検出する素子であり、例えば、歪ゲージ抵抗式、半導体ピエゾ抵抗式、又は、静電容量式等の素子が用いられる。半導体基板23の表面は平面になっており、この平面が圧力を検出する検出面26を構成する。検出面26に垂直な方向が方向Zである。 The sensor chip 22 includes a semiconductor substrate 23 such as a silicon single crystal or a single crystal of a compound semiconductor such as gallium-arsenic. The semiconductor substrate 23 has a rectangular shape whose direction is the longitudinal direction. On the surface of the semiconductor substrate 23, an element array 25 including a plurality of pressure detection elements 24 arranged along the direction X is formed. The pressure detection element 24 is an element that detects strain applied to the element as a pressure signal, and for example, a strain gauge resistance type, a semiconductor piezoresistance type, or an electrostatic capacitance type element is used. The surface of the semiconductor substrate 23 is a flat surface, and this flat surface constitutes a detection surface 26 for detecting pressure. The direction perpendicular to the detection surface 26 is the direction Z.

半導体基板23の表面の方向Xの両端部には、各圧力検出素子24と電気的に接続された電極パッドからなるチップ側端子部27が形成されている(図4参照)。 Chip-side terminal portions 27, which are electrode pads electrically connected to the respective pressure detection elements 24, are formed at both ends of the surface of the semiconductor substrate 23 in the direction X (see FIG. 4 ).

基板50は、セラミック基板又はガラス基板等の半導体基板23よりも十分に剛性の高い硬質基板により構成されている。基板50は、方向Xが長手方向となる矩形状となっている。 The substrate 50 is formed of a hard substrate having a sufficiently higher rigidity than the semiconductor substrate 23 such as a ceramic substrate or a glass substrate. The substrate 50 has a rectangular shape whose direction X is the longitudinal direction.

図5に示すように、半導体基板23の検出面26の反対面には、検出面26に垂直な方向Zに凹む凹部が形成されている。半導体基板23は、この凹部によって、方向Zにおける厚みが他の部分よりも薄い薄肉部(ダイヤフラム)を有する構成となっている。 As shown in FIG. 5, a recessed portion that is recessed in the direction Z perpendicular to the detection surface 26 is formed on the surface opposite to the detection surface 26 of the semiconductor substrate 23. The semiconductor substrate 23 is configured to have a thin portion (diaphragm) whose thickness in the direction Z is thinner than other portions due to the recess.

半導体基板23の検出面26の反対面のうち凹部を除く部分は、接着材29によって基板50の凹部51の底面52に固定されている。接着材29は、例えば紫外線硬化樹脂が用いられる。 A portion of the surface of the semiconductor substrate 23 opposite to the detection surface 26 except the concave portion is fixed to the bottom surface 52 of the concave portion 51 of the substrate 50 with an adhesive 29. As the adhesive material 29, for example, an ultraviolet curable resin is used.

半導体基板23の凹部が、基板50の凹部51の底面52に形成された貫通孔54のみによって大気と連通するように、半導体基板23は基板50の凹部51の底面に固定されている。 The semiconductor substrate 23 is fixed to the bottom surface of the recess 51 of the substrate 50 so that the recess of the semiconductor substrate 23 communicates with the atmosphere only through the through hole 54 formed in the bottom surface 52 of the recess 51 of the substrate 50.

図5に示すように、フレキシブル基板21には、基板50の貫通孔54と対向する位置に貫通孔211が形成されている。この貫通孔211は、ベース30のベース貫通孔33と連通している。これにより、ベース貫通孔33、貫通孔211、及び、貫通孔54によって、半導体基板23の凹部内が大気圧に保たれるようになっている。 As shown in FIG. 5, a through hole 211 is formed in the flexible substrate 21 at a position facing the through hole 54 of the substrate 50. The through hole 211 communicates with the base through hole 33 of the base 30. As a result, the base through hole 33, the through hole 211, and the through hole 54 keep the inside of the recess of the semiconductor substrate 23 at atmospheric pressure.

図4に示すように、基板50の方向Xの両端部のうち、凹部51が形成された面には、チップ側端子部27の各電極パッドと電気的に接続するための電極パッドからなる基板側端子部53が設けられている。 As shown in FIG. 4, a substrate including electrode pads for electrically connecting to the electrode pads of the chip-side terminal portion 27 on the surface of the substrate 50 in which the recess 51 is formed, in both ends in the direction X. The side terminal portion 53 is provided.

図5に示すように、チップ側端子部27の電極パッドと基板側端子部53の電極パッドは、金又はアルミニウム等の導電部材28により接続されている。導電部材28は、樹脂等の絶縁材料からなる保護部材281によって周囲を覆われて保護されている。基板50の凹部51の側面と、半導体基板23及び接着材29との間は、保護部材281よりも温度及び湿度による体積変化の少ない材料282によって埋められている。 As shown in FIG. 5, the electrode pads of the chip-side terminal portion 27 and the electrode pads of the substrate-side terminal portion 53 are connected by a conductive member 28 such as gold or aluminum. The periphery of the conductive member 28 is covered and protected by a protection member 281 made of an insulating material such as resin. The space between the side surface of the recess 51 of the substrate 50 and the semiconductor substrate 23 and the adhesive material 29 is filled with a material 282 whose volume change less than that of the protective member 281 due to temperature and humidity.

次に、保護カバー40の詳細について説明する。 Next, details of the protective cover 40 will be described.

保護カバー40の頂面41は、センサチップ22の検出面26に垂直な方向Zにおいて圧力検出素子24よりもセンサチップ22と基板50との固定箇所(接着材29のある場所)側とは反対側に配置されかつ検出面26に平行な面である。2つの面が平行であるとは、2つの面のなす角度が0度を中心とする公差を含めた範囲に納まっている状態をいう。同様に、2つの面が垂直であるとは、この2つの面のなす角度が90度を中心とする公差を含めた範囲に納まっている状態をいう。 The top surface 41 of the protective cover 40 is opposite to the side where the sensor chip 22 and the substrate 50 are fixed (the place where the adhesive 29 is located) side of the pressure detection element 24 in the direction Z perpendicular to the detection surface 26 of the sensor chip 22. It is a surface arranged on the side and parallel to the detection surface 26. The two surfaces being parallel means a state in which the angle formed by the two surfaces is within a range including a tolerance centered on 0 degree. Similarly, the two surfaces being vertical means that the angle formed by the two surfaces is within a range including a tolerance centering on 90 degrees.

保護カバー40には、頂面41のうちの各センサチップ22の検出面26と対向する位置から該検出面26側に向かって貫通する開口部42が形成されている。方向Zに見た平面視において、素子列25の全体は開口部42と重なっている。 The protective cover 40 is provided with an opening 42 that penetrates from the position of the top surface 41 facing the detection surface 26 of each sensor chip 22 toward the detection surface 26 side. When viewed in a plan view in the direction Z, the entire element row 25 overlaps the opening 42.

保護カバー40の内周面と、ベース30、センサ部20、及び、フレキシブル基板21とによって囲まれた空間には、図5に示すように充填材55が充填されている。 A space surrounded by the inner peripheral surface of the protective cover 40, the base 30, the sensor unit 20, and the flexible substrate 21 is filled with a filler 55 as shown in FIG.

充填材55は、保護カバー40の開口部42にも充填されており、充填材55の外部に露出する表面551は保護カバー40の頂面41と同一面に形成されている。この表面551は、開口部42の開口面を構成している。充填材55の表面551と保護カバー40の頂面41によって形成される平面は、検出面26と平行になっており、被測定者の体表面に接触する接触面を形成する。 The filling material 55 is also filled in the opening 42 of the protective cover 40, and the surface 551 exposed to the outside of the filling material 55 is formed on the same surface as the top surface 41 of the protective cover 40. The surface 551 constitutes an opening surface of the opening 42. The plane formed by the surface 551 of the filling material 55 and the top surface 41 of the protective cover 40 is parallel to the detection surface 26 and forms a contact surface that comes into contact with the body surface of the measurement subject.

充填材55は、保護カバー40よりも硬度が低い材料が使用されることが好ましい。例えば、保護カバー40の材料として好ましくはセラミックが用いられ、充填材55としてはセラミックよりも硬度の低いエポキシ樹脂又はシリコーン樹脂等が用いられる。 The filler 55 is preferably made of a material having a hardness lower than that of the protective cover 40. For example, a ceramic is preferably used as the material of the protective cover 40, and an epoxy resin or a silicone resin having a hardness lower than that of the ceramic is used as the filler 55.

図5に示すように、頂面41と重なりかつ方向Xに伸びる直線での断面において、保護カバー40の傾斜面44は、頂面41の方向Xの両端縁45xと連続し、かつ、表面551に対して方向Zのセンサチップ22に近づく方向に傾斜角θで傾斜した面である。 As shown in FIG. 5, in the cross section of the straight line that overlaps the top surface 41 and extends in the direction X, the inclined surface 44 of the protective cover 40 is continuous with both end edges 45x of the top surface 41 in the direction X, and the surface 551. With respect to the sensor chip 22 in the direction Z, the surface is inclined at an inclination angle θ.

また、図5に示すように、保護カバー40の垂直面46は、傾斜面44と連続しかつ表面551に垂直な面である。垂直面46は、方向Zにおいて表面551よりもセンサチップ22側に位置し、かつ、方向Zにみた平面視において頂面41の端縁45よりも外側に位置している。 Further, as shown in FIG. 5, the vertical surface 46 of the protective cover 40 is a surface continuous with the inclined surface 44 and perpendicular to the surface 551. The vertical surface 46 is located closer to the sensor chip 22 than the surface 551 in the direction Z, and is located outside the edge 45 of the top surface 41 in a plan view seen in the direction Z.

なお、図3の圧脈波センサ10の方向Yに伸びかつ頂面41を通る直線での断面における保護カバー40の形状は、図5に示した保護カバー40の形状と同様である。つまり、保護カバー40の外周面は、頂面41と、頂面41の方向Yの両端縁と連続する面であって、頂面41に対してセンサチップ22に近づく方向に傾斜した傾斜面44と、傾斜面44に連続する垂直面46とを有する。 The shape of the protective cover 40 in a cross section taken along a straight line extending in the direction Y of the pressure pulse wave sensor 10 and passing through the top surface 41 of FIG. 3 is similar to the shape of the protective cover 40 shown in FIG. That is, the outer peripheral surface of the protective cover 40 is a surface that is continuous with the top surface 41 and both edges of the top surface 41 in the direction Y, and is an inclined surface 44 that is inclined with respect to the top surface 41 in the direction toward the sensor chip 22. And a vertical surface 46 continuous with the inclined surface 44.

方向Xと方向Yのそれぞれにおけるベース30の両端部の側面31は、保護カバー40が固定された状態で保護カバー40の垂直面46と段差なく接続されており、垂直面46と側面31は方向Zに水平な同一面を形成している。 The side surfaces 31 at both ends of the base 30 in each of the direction X and the direction Y are connected to the vertical surface 46 of the protective cover 40 without a step in the state where the protective cover 40 is fixed, and the vertical surface 46 and the side surface 31 are in the direction. The same plane that is horizontal to Z is formed.

図6は、図3に示す圧脈波センサ10を方向Zから見た平面図である。図6では、センサ部20については導電部材28の位置のみを図示して他の構成要素を省略している。 FIG. 6 is a plan view of the pressure pulse wave sensor 10 shown in FIG. 3 viewed from the direction Z. In FIG. 6, only the position of the conductive member 28 of the sensor unit 20 is shown and other components are omitted.

図6に示すように、センサ部20の導電部材28は、方向Zに見た平面視において、頂面41の端縁45と重ならない位置に配置されている。 As shown in FIG. 6, the conductive member 28 of the sensor unit 20 is arranged at a position where it does not overlap the edge 45 of the top surface 41 in the plan view seen in the direction Z.

頂面41の端縁45は、頂面41が体表面に対して押圧された状態において応力が最も大きく加わる部分である。一方、導電部材28は、ワイヤボンディング等で形成されているため、大きな力が加わると断線の可能性がある。 The edge 45 of the top surface 41 is a portion to which the stress is most applied when the top surface 41 is pressed against the body surface. On the other hand, since the conductive member 28 is formed by wire bonding or the like, there is a possibility of disconnection when a large force is applied.

図6に示すように、頂面41の端縁45と重ならない位置に導電部材28があることで、応力が大きく加わる部分の下方には導電部材28が存在しない。このため、圧脈波センサ10を体表面に押圧した場合でも、導電部材28に加わる力を小さくすることができ、断線を防止することができる。 As shown in FIG. 6, since the conductive member 28 is located at a position where it does not overlap the edge 45 of the top surface 41, the conductive member 28 does not exist below the portion where a large amount of stress is applied. Therefore, even when the pressure pulse wave sensor 10 is pressed against the body surface, it is possible to reduce the force applied to the conductive member 28 and prevent disconnection.

なお、図6では、導電部材28が端縁45の内側に存在しているが、導電部材28が端縁45の外側に存在する構成であっても同様の効果が得られる。 Although the conductive member 28 is present inside the end edge 45 in FIG. 6, the same effect can be obtained even if the conductive member 28 is present outside the end edge 45.

図1に示した生体情報測定装置100の回転機構61は、方向Xに伸びる軸と方向Yに伸びる軸の2つの軸の各々の周りに圧脈波センサ10を回転させるための機構である。 The rotation mechanism 61 of the biological information measuring device 100 shown in FIG. 1 is a mechanism for rotating the pressure pulse wave sensor 10 around each of two axes, an axis extending in the direction X and an axis extending in the direction Y.

以上のように構成された生体情報測定装置100は、方向Xが圧脈波の検出対象となる手首の橈骨動脈T(図1参照)と交差するように手首に装着して使用される。 The biological information measuring device 100 configured as described above is used by being attached to the wrist such that the direction X intersects with the radial artery T of the wrist (see FIG. 1) that is the target of pressure pulse wave detection.

手首に生体情報測定装置100が装着され、測定開始指示がなされると、制御部は、空気袋70の内圧を増加させて、圧脈波センサ10を手首の表面に対して押圧する。 When the biological information measuring device 100 is attached to the wrist and a measurement start instruction is given, the control unit increases the internal pressure of the air bag 70 and presses the pressure pulse wave sensor 10 against the surface of the wrist.

制御部は、圧脈波の検出精度が最大となるように圧脈波センサ10の方向Xに伸びる軸と方向Yに伸びる軸の2つの軸の各々の周りの回転角度を決定する。 The control unit determines the rotation angle around each of the two axes of the pressure pulse wave sensor 10 extending in the direction X and the axis extending in the direction Y so that the detection accuracy of the pressure pulse wave is maximized.

制御部は、圧脈波センサ10を上記決定した回転角度で回転させ、所定の押圧力で体表面に圧脈波センサ10を押圧した状態で、圧脈波センサ10の圧力検出素子24によって圧脈波を検出し、検出した圧脈波に基づいて生体情報を算出し記憶する。 The control unit rotates the pressure pulse wave sensor 10 at the determined rotation angle, presses the pressure pulse wave sensor 10 against the body surface with a predetermined pressing force, and applies pressure by the pressure detection element 24 of the pressure pulse wave sensor 10. A pulse wave is detected, and biological information is calculated and stored based on the detected pressure pulse wave.

以上のように、圧脈波センサ10によれば、センサチップ22の検出面26よりも上方に保護カバー40の開口部42が設けられ、この開口部42が充填材55によって埋められて、保護カバー40の頂面41と充填材55の表面551とにより、体表面との接触面が形成される。 As described above, according to the pressure pulse wave sensor 10, the opening 42 of the protective cover 40 is provided above the detection surface 26 of the sensor chip 22, and the opening 42 is filled with the filling material 55 to protect it. The top surface 41 of the cover 40 and the surface 551 of the filler 55 form a contact surface with the body surface.

このように、体表面に押圧される接触面が保護カバー40と充填材55とによって構成されているため、圧脈波センサ10のセンサチップ22の耐久性を向上させることができる。したがって、生体情報測定装置100を長い期間にわたって手首に装着して使用することが可能となる。保護カバー40として充填材55よりも硬度の高い材料を用いることで、耐久性をより向上させることができる。 As described above, since the contact surface pressed against the body surface is composed of the protective cover 40 and the filler 55, the durability of the sensor chip 22 of the pressure pulse wave sensor 10 can be improved. Therefore, the biological information measuring device 100 can be worn on the wrist and used for a long period of time. By using a material having a hardness higher than that of the filler 55 as the protective cover 40, the durability can be further improved.

また、圧脈波センサ10によれば、充填材55の表面551は、頂面41の平坦性を利用して容易に平坦にすることができる。このため、製造コストを削減することができる。保護カバー40として充填材55よりも硬度の高い材料を用いた場合には、充填材55の表面551をより容易に平坦にすることができる。 Further, according to the pressure pulse wave sensor 10, the surface 551 of the filler 55 can be easily flattened by utilizing the flatness of the top surface 41. Therefore, the manufacturing cost can be reduced. When a material having a hardness higher than that of the filler 55 is used as the protective cover 40, the surface 551 of the filler 55 can be flattened more easily.

また、圧脈波センサ10は、保護カバー40が、頂面41の方向Xの両端縁45xに連続する傾斜面44を有する構成である。この構成によれば、回転駆動部60によって圧脈波センサ10を方向Yに伸びる軸の周り(手首周り)に回転させた場合に、保護カバー40の体表面に当たる面積を減らすことができる。 Further, the pressure pulse wave sensor 10 is configured such that the protective cover 40 has an inclined surface 44 that is continuous with both end edges 45x of the top surface 41 in the direction X. According to this configuration, when the pressure pulse wave sensor 10 is rotated by the rotation drive unit 60 around the axis extending in the direction Y (around the wrist), the area of the protective cover 40 that contacts the body surface can be reduced.

生体情報測定装置100は、保護カバー40の頂面41が橈骨動脈Tの上方に位置するように手首に装着されるが、橈骨動脈Tの周囲には橈骨又は腱等の硬い組織が存在する。 The biological information measuring device 100 is attached to the wrist so that the top surface 41 of the protective cover 40 is located above the radial artery T, but a hard tissue such as a radius or tendon exists around the radial artery T.

圧脈波センサ10が手首周りに回転した場合には、保護カバー40の傾斜面44がこれら固い組織からの圧力を逃がすことができるため、生体情報測定装置100の装着感を向上させることができる。また、圧脈波センサ10の回転動作が硬い組織に邪魔されにくくなることで、少ない駆動力及び押圧力で所望の回転角度を維持することが可能となる。 When the pressure pulse wave sensor 10 rotates around the wrist, the inclined surface 44 of the protective cover 40 can release the pressure from these hard tissues, so that the wearing comfort of the biological information measuring device 100 can be improved. .. Further, since the rotation operation of the pressure pulse wave sensor 10 is less likely to be disturbed by the hard tissue, it is possible to maintain a desired rotation angle with a small driving force and pressing force.

なお、保護カバー40の傾斜面44は平面ではなく曲面であってもよい。つまり、保護カバー40は、頂面41と垂直面46とを繋ぐ曲面を有する構成であってもよい。この曲面は、頂面41の方向Xの両端縁と連続し、かつ、表面551及び表面551に垂直な面の各々と交差する面を構成する。このように、傾斜面44が曲面で構成されている場合でも、圧脈波センサ10が手首周りに回転した場合には、保護カバー40の曲面がこれら固い組織からの圧力を逃がすことができるため、生体情報測定装置100の装着感を向上させることができる。 The inclined surface 44 of the protective cover 40 may be a curved surface instead of a flat surface. That is, the protective cover 40 may have a curved surface that connects the top surface 41 and the vertical surface 46. The curved surface forms a surface that is continuous with both edges of the top surface 41 in the direction X and that intersects the surface 551 and each of the surfaces perpendicular to the surface 551. As described above, even when the inclined surface 44 is formed of a curved surface, the curved surface of the protective cover 40 can release the pressure from these hard tissues when the pressure pulse wave sensor 10 rotates around the wrist. Therefore, the wearing feeling of the biological information measuring device 100 can be improved.

なお、図5に示した傾斜面44の傾斜角θは、回転機構61によって圧脈波センサ10を方向Yに伸びる軸の周りに回転させることのできる回転角度(空気袋70による圧脈波センサ10の押圧方向に対して検出面26が垂直な状態を基準としたときの回転角度)の最大値未満の値としておくことが好ましい。 The inclination angle θ of the inclined surface 44 shown in FIG. 5 is a rotation angle at which the pressure pulse wave sensor 10 can be rotated by the rotation mechanism 61 around an axis extending in the direction Y (pressure pulse wave sensor by the air bag 70). It is preferable to set a value smaller than the maximum value of the rotation angle (when the detection surface 26 is perpendicular to the pressing direction of 10).

このような値にしておくことで、圧脈波センサ10を手首周りに最大限回転させた場合でも、傾斜面44が体表面に接触するのを防いで、回転動作を円滑に行うことができる。 By setting such a value, even when the pressure pulse wave sensor 10 is rotated to the maximum around the wrist, the inclined surface 44 is prevented from coming into contact with the body surface, and the rotation operation can be smoothly performed. ..

また、圧脈波センサ10は、保護カバー40が垂直面46を有する構成である。センサチップ22は、圧力検出素子24により検出される歪みの信号を圧力値に変換するのに必要な校正データ取得のために、製造工程において、頂面41及び表面551から構成される接触面を密閉容器におさめた状態で、接触面に圧力をかけて圧力検出素子24から信号を取得する作業を行う必要がある。 Further, the pressure pulse wave sensor 10 has a configuration in which the protective cover 40 has a vertical surface 46. In order to obtain the calibration data necessary for converting the strain signal detected by the pressure detection element 24 into a pressure value, the sensor chip 22 has a contact surface composed of the top surface 41 and the surface 551 in the manufacturing process. It is necessary to perform a work of applying a pressure to the contact surface and acquiring a signal from the pressure detection element 24 in a state of being housed in a closed container.

保護カバー40において表面551よりもベース30側に垂直面46があることで、この垂直面46の周りにキャップ状の器具を取り付けて、この器具内を容易に密閉することができる。したがって、校正データの生成作業が容易となり、製造コストを削減することができる。 Since the protective cover 40 has the vertical surface 46 closer to the base 30 than the surface 551, a cap-shaped device can be attached around the vertical surface 46 to easily seal the inside of the device. Therefore, the work of generating the calibration data is facilitated, and the manufacturing cost can be reduced.

図7は、図2に示す圧脈波センサ10の保護カバー40の変形例である保護カバー401の外観構成を示す斜視図である。 FIG. 7 is a perspective view showing an external configuration of a protective cover 401 which is a modified example of the protective cover 40 of the pressure pulse wave sensor 10 shown in FIG.

保護カバー401は、保護カバー40の方向Yの両端面が表面551に垂直な垂直面46に変更された構成である。垂直面46は、頂面41の方向Yの端縁と連続する面である。 The protective cover 401 has a configuration in which both end surfaces of the protective cover 40 in the direction Y are changed to vertical surfaces 46 which are perpendicular to the surface 551. The vertical surface 46 is a surface that is continuous with the edge of the top surface 41 in the direction Y.

保護カバー401の構成によれば、頂面41の方向Yの端縁がセンサチップ22から離れた位置にあるため、センサチップ22に加わる応力を減らすことができ、圧脈波検出精度の向上、圧脈波センサ10の耐久性向上が可能となる。 According to the configuration of the protective cover 401, since the edge of the top surface 41 in the direction Y is located away from the sensor chip 22, the stress applied to the sensor chip 22 can be reduced, and the pressure pulse wave detection accuracy can be improved. The durability of the pressure pulse wave sensor 10 can be improved.

圧脈波センサ10の保護カバー40の外周面は、頂面41と、頂面41の端縁45と連続しかつ表面551に垂直な垂直面46とのみで構成されていてもよい。つまり、保護カバー40の外周面の傾斜面44は必須ではない。 The outer peripheral surface of the protective cover 40 of the pressure pulse wave sensor 10 may be configured only by the top surface 41 and the vertical surface 46 that is continuous with the edge 45 of the top surface 41 and is perpendicular to the surface 551. That is, the inclined surface 44 on the outer peripheral surface of the protective cover 40 is not essential.

図8は、図2に示す圧脈波センサ10の変形例である圧脈波センサ12の断面模式図である。 FIG. 8 is a schematic sectional view of a pressure pulse wave sensor 12 which is a modified example of the pressure pulse wave sensor 10 shown in FIG.

図8に示す圧脈波センサ12は、保護カバー40の外周面が、頂面41と、頂面41の端縁と連続する垂直面46とにより構成され、保護カバー40の外周面が傾斜面44を有しない点が図5に示す構成とは異なる。その他の構成は、圧脈波センサ10と同様であり、同様の作用・効果を得ることができる。図8に示す構成では、方向Zに見た平面視において、頂面41の端縁と垂直面46とは重なっている。 In the pressure pulse wave sensor 12 shown in FIG. 8, the outer peripheral surface of the protective cover 40 is composed of a top surface 41 and a vertical surface 46 continuous with the edge of the top surface 41, and the outer peripheral surface of the protective cover 40 is an inclined surface. The difference from the configuration shown in FIG. Other configurations are the same as those of the pressure pulse wave sensor 10, and the same actions and effects can be obtained. In the configuration shown in FIG. 8, the edge of the top surface 41 and the vertical surface 46 overlap each other when seen in the plan view in the direction Z.

圧脈波センサ10及び圧脈波センサ12に搭載されるセンサ部20の構成は、図1及び図8に示したものには限定されない。例えば、センサ部20を図9に示したセンサ部201に変更してもよい。 The configurations of the sensor units 20 mounted on the pressure pulse wave sensor 10 and the pressure pulse wave sensor 12 are not limited to those shown in FIGS. 1 and 8. For example, the sensor unit 20 may be changed to the sensor unit 201 shown in FIG.

センサ部201は、基板50が平板状の基板501に変更された点を除いては、センサ部20と同じ構成である。このようなセンサ部201を用いた場合でも、上述してきた効果を得ることができる。 The sensor unit 201 has the same configuration as the sensor unit 20 except that the substrate 50 is changed to a flat plate-shaped substrate 501. Even when such a sensor unit 201 is used, the effects described above can be obtained.

今回開示された実施形態はすべての点で例示であって制限的なものではないと考えられるべきである。本発明の範囲は上記した説明ではなくて特許請求の範囲によって示され、特許請求の範囲と均等の意味及び範囲内でのすべての変更が含まれることが意図される。 The embodiments disclosed this time are to be considered as illustrative in all points and not restrictive. The scope of the present invention is shown not by the above description but by the claims, and is intended to include meanings equivalent to the claims and all modifications within the scope.

例えば、圧脈波センサ10は、センサ部20を2つ有するものとしたが、センサ部20を1つだけ有する構成であってもよい。この場合には、回転機構61が、圧脈波センサ10を方向Yに伸びる軸の周りにのみ回転させるための機構に変更される。 For example, although the pressure pulse wave sensor 10 has two sensor units 20, it may have a configuration having only one sensor unit 20. In this case, the rotation mechanism 61 is changed to a mechanism for rotating the pressure pulse wave sensor 10 only around the axis extending in the direction Y.

圧脈波センサ10がセンサ部20を1つだけ有する構成の場合は、センサ部20のセンサチップ22の表面には1つの圧力検出素子24だけが形成されていてもよい。この場合には、回転駆動部60は省略することができる。 When the pressure pulse wave sensor 10 is configured to have only one sensor unit 20, only one pressure detection element 24 may be formed on the surface of the sensor chip 22 of the sensor unit 20. In this case, the rotary drive unit 60 can be omitted.

また、圧脈波センサ10は、方向Yに配列された3つ以上のセンサ部20を有する構成であってもよい。 The pressure pulse wave sensor 10 may have a configuration including three or more sensor units 20 arranged in the direction Y.

また、保護カバー40の頂面41は検出面26に平行な面とされているが、図10に示すように、保護カバー40の頂面41は検出面26に対して傾斜していてもよい。図10に示す変形例においても、頂面41に形成された開口部42は充填材55によって埋められており、この開口部42の開口面は検出面26と平行になっている。このような構成であっても耐久性を向上させることができる。 Although the top surface 41 of the protective cover 40 is parallel to the detection surface 26, the top surface 41 of the protection cover 40 may be inclined with respect to the detection surface 26 as shown in FIG. .. Also in the modification shown in FIG. 10, the opening 42 formed in the top surface 41 is filled with the filling material 55, and the opening surface of the opening 42 is parallel to the detection surface 26. Even with such a configuration, durability can be improved.

以上では、手首に装着して使用される生体情報測定装置100を説明したが、動脈が通る生体部位に装着するタイプの生体情報測定装置であれば本発明を適用可能である。 Although the biological information measuring device 100 to be worn on the wrist has been described above, the present invention can be applied to any biological information measuring device of a type to be attached to a living body part through which an artery passes.

以上説明してきたように、本明細書には以下の事項が開示されている。 As described above, the following items are disclosed in this specification.

開示された圧脈波センサは、圧力検出素子を有するセンサチップと、前記センサチップが固定される基板と、前記基板及び前記センサチップを保護する保護部材と、を備え、前記保護部材は、前記センサチップの前記圧力検出素子が形成された検出面に垂直な方向である垂直方向において前記圧力検出素子よりも前記センサチップと前記基板との固定箇所側とは反対側の前記検出面と対向する位置に配置された開口部を有し、前記開口部と前記検出面との間には充填材が充填されているものである。 The disclosed pressure pulse wave sensor includes a sensor chip having a pressure detection element, a substrate to which the sensor chip is fixed, and a protection member that protects the substrate and the sensor chip, and the protection member is the In the vertical direction, which is a direction perpendicular to the detection surface on which the pressure detection element is formed, of the sensor chip, the pressure detection element faces the detection surface on the side opposite to the side where the sensor chip and the substrate are fixed. It has an opening arranged at a position, and a filling material is filled between the opening and the detection surface.

開示された圧脈波センサは、前記保護部材は、前記充填材よりも硬度が高い材料で構成されているものである。 In the disclosed pressure pulse wave sensor, the protective member is made of a material having a hardness higher than that of the filling material.

開示された圧脈波センサは、前記保護部材はセラミックによって構成されているものである。 In the disclosed pressure pulse wave sensor, the protection member is made of ceramic.

開示された圧脈波センサは、前記保護部材の外周面は、前記開口部の開口面に垂直な垂直面を有し、前記垂直面は、前記垂直方向において前記開口面よりも前記センサチップ側に位置し、かつ、前記垂直方向にみた平面視において前記保護部材の前記開口部が形成された頂面の端縁と重なる又は前記頂面の端縁よりも外側に位置するものである。 In the disclosed pressure pulse wave sensor, the outer peripheral surface of the protection member has a vertical surface perpendicular to the opening surface of the opening, and the vertical surface is closer to the sensor chip than the opening surface in the vertical direction. And is overlapped with the edge of the top surface of the protective member in which the opening is formed or outside the edge of the top surface when viewed in a plan view in the vertical direction.

開示された圧脈波センサは、前記センサチップは、一方向に並ぶ複数の前記圧力検出素子からなる素子列を有し、前記保護部材の外周面は、前記開口部が形成された頂面の前記一方向の両端縁と連続する面であって、前記開口部の開口面及び前記開口面に垂直な面の各々と交差する面を有するものである。 The disclosed pressure pulse wave sensor, the sensor chip has an element row consisting of a plurality of the pressure detection elements arranged in one direction, the outer peripheral surface of the protective member, the top surface in which the opening is formed. It has a surface which is continuous with both end edges in the one direction and which intersects with each of the opening surface of the opening and the surface perpendicular to the opening surface.

開示された圧脈波センサは、前記基板に設けられ、前記センサチップの前記一方向の端部に設けられた端子部と電気的に接続するための基板側端子部と、前記センサチップの端子部と前記基板側端子部とを接続する導電部材と、を更に備え、前記導電部材は、前記垂直方向にみた平面視において前記頂面の端縁と重ならない位置に配置されているものである。 The disclosed pressure pulse wave sensor is provided on the substrate, a substrate-side terminal portion for electrically connecting to a terminal portion provided on the end portion in the one direction of the sensor chip, and a terminal of the sensor chip. And a conductive member that connects the board-side terminal portion to each other, and the conductive member is arranged at a position that does not overlap an edge of the top surface when viewed in a plan view in the vertical direction. ..

開示された圧脈波センサは、前記保護部材の外周面は、前記頂面の前記一方向及び前記垂直方向の各々に直交する方向の両端縁と連続する面であって、前記開口部の開口面に対して垂直な垂直面を有するものである。 In the disclosed pressure pulse wave sensor, the outer peripheral surface of the protection member is a surface that is continuous with both end edges of the top surface in a direction orthogonal to each of the one direction and the vertical direction, and the opening of the opening portion. It has a vertical surface perpendicular to the surface.

開示された脈波検出装置は、前記圧脈波センサと、前記圧脈波センサを前記一方向及び前記垂直方向の各々に直交する方向の周りに回転させる回転機構と、を備え、前記面は前記開口面に対して傾斜した傾斜面であり、前記傾斜面の傾斜角度は、前記回転機構によって前記圧脈波センサが回転可能な回転角の最大値未満になっているものである。 The disclosed pulse wave detection device includes the pressure pulse wave sensor, and a rotation mechanism that rotates the pressure pulse wave sensor around a direction orthogonal to each of the one direction and the vertical direction, and the surface is It is an inclined surface inclined with respect to the opening surface, and the inclination angle of the inclined surface is less than the maximum value of the rotation angle at which the pressure pulse wave sensor can be rotated by the rotation mechanism.

開示された生体情報測定装置は、前記脈波検出装置と、前記圧脈波センサによって検出された圧脈波に基づいて生体情報を算出する生体情報算出部と、を備えるものである。 The disclosed biological information measurement device includes the pulse wave detection device and a biological information calculation unit that calculates biological information based on the pressure pulse wave detected by the pressure pulse wave sensor.

開示された生体情報測定装置は、前記圧脈波センサと、前記圧脈波センサによって検出された圧脈波に基づいて生体情報を算出する生体情報算出部と、を備えるものである。 The disclosed biological information measuring device includes the pressure pulse wave sensor and a biological information calculation unit that calculates biological information based on the pressure pulse wave detected by the pressure pulse wave sensor.

100 生体情報測定装置
10、12 圧脈波センサ
60 回転駆動部
61 回転機構
62 アクチュエータ
70 空気袋
80 筐体
T 橈骨動脈
20 センサ部
21 フレキシブル基板
211 貫通孔
22 センサチップ
23 半導体基板
24 圧力検出素子
25 素子列
26 検出面
27 チップ側端子部
28 導電部材
281 保護部材
282 材料
29 接着材
30 ベース
31 側面
32 載置面
33 ベース貫通孔
34 開口
40,401 保護カバー
41 頂面
42 開口部
44 傾斜面
45,45x 端縁
46 垂直面
50、501 基板
51 凹部
52 底面
53 基板側端子部
54 貫通孔
55 充填材
551 表面(開口面)
θ 傾斜角
X,Y,Z 方向
100 Biological information measuring device 10, 12 Pressure pulse wave sensor 60 Rotation drive part 61 Rotation mechanism 62 Actuator 70 Air bag 80 Housing T Radial artery 20 Sensor part 21 Flexible substrate 211 Through hole 22 Sensor chip 23 Semiconductor substrate 24 Pressure detection element 25 Element row 26 Detection surface 27 Chip-side terminal portion 28 Conductive member 281 Protective member 282 Material 29 Adhesive material 30 Base 31 Side surface 32 Mounting surface 33 Base through hole 34 Opening 40, 401 Protective cover 41 Top surface 42 Opening portion 44 Slope 45 , 45x edge 46 vertical surfaces 50, 501 substrate 51 recessed portion 52 bottom surface 53 substrate side terminal portion 54 through hole 55 filler 551 surface (opening surface)
θ Tilt angle X, Y, Z direction

Claims (6)

橈骨動脈と交差する一方向に並ぶ複数の圧力検出素子からなる素子列を有するセンサチップと、前記センサチップが固定される基板と、を含むセンサ部と、
前記センサ部を保護する保護部材と、
前記圧力検出素子が形成された前記センサチップの検出面と前記保護部材に設けられた開口部との間に充填されている充填と、を有し、
前記開口部が、前記センサチップの前記基板に固定された側の反対側であって前記検出面に垂直な垂直方向において前記検出面と対向する位置に配置されている、圧脈波センサと、
前記圧脈波センサを前記一方向及び前記垂直方向直交する方向の周りに回転させる回転機構と、を備え、
前記保護部材の外周面は、
前記開口部が形成された頂面と、
前記頂面の前記一方向の両端縁と連続する面であって、前記開口部の開口面に対して傾斜した傾斜面と、を有し、
前記傾斜面の傾斜角度は、前記回転機構によって前記圧脈波センサが回転可能な回転角の最大値未満になっている脈波検出装置。
A sensor unit including a sensor chip having an element row composed of a plurality of pressure detection elements arranged in one direction intersecting with the radial artery, and a substrate to which the sensor chip is fixed ,
A protection member for protecting the sensor section ,
A filling material filled between the detection surface of the sensor chip on which the pressure detection element is formed and the opening provided in the protection member, and
The pressure pulse wave sensor, wherein the opening is arranged at a position opposite to the detection surface in a vertical direction perpendicular to the detection surface on the side opposite to the side of the sensor chip fixed to the substrate,
And a rotation mechanism for rotating around a direction perpendicular to said pressure pulse wave sensor in the one direction and the vertical direction,
The outer peripheral surface of the protective member is
A top surface on which the opening is formed,
A surface that is continuous with both edges in the one direction of the top surface, and an inclined surface that is inclined with respect to the opening surface of the opening,
The pulse wave detection device, wherein the inclination angle of the inclined surface is less than the maximum value of the rotation angle at which the pressure pulse wave sensor can be rotated by the rotation mechanism.
請求項1記載の脈波検出装置であって、
前記保護部材は、前記充填材よりも硬度が高い材料で構成されている脈波検出装置。
The pulse wave detection device according to claim 1, wherein
The pulse wave detecting device, wherein the protective member is made of a material having a hardness higher than that of the filling material.
請求項2記載の脈波検出装置であって、
前記保護部材はセラミックによって構成されている脈波検出装置。
The pulse wave detection device according to claim 2,
The pulse wave detecting device, wherein the protective member is made of ceramic.
請求項1〜3のいずれか1項記載の脈波検出装置であって、
前記保護部材の外周面は、更に前記開口部の開口面に垂直な垂直面を有し、
前記垂直面は、前記垂直方向において前記開口面よりも前記センサチップ側に位置し、かつ、前記垂直方向にみた平面視において前記保護部材の前記頂面の端縁と重なる又は前記頂面の端縁よりも外側に位置する脈波検出装置。
The pulse wave detection device according to any one of claims 1 to 3,
The outer peripheral surface of the protective member further has a vertical surface perpendicular to the opening surface of the opening,
The vertical surface is located closer to the sensor chip than the opening surface in the vertical direction, and overlaps with an edge of the top surface of the protection member in plan view viewed in the vertical direction, or an end of the top surface. A pulse wave detection device located outside the edge.
請求項1〜4のいずれか1項記載の脈波検出装置であって、
前記基板に設けられ、前記センサチップの前記一方向の端部に設けられた端子部と電気的に接続するための基板側端子部と、
前記センサチップの端子部と前記基板側端子部とを接続する導電部材と、を更に備え、
前記導電部材は、前記垂直方向にみた平面視において前記頂面の端縁と重ならない位置に配置されている脈波検出装置。
The pulse wave detection device according to any one of claims 1 to 4,
A substrate-side terminal portion provided on the substrate and electrically connected to a terminal portion provided on the end portion in the one direction of the sensor chip,
Further comprising a conductive member connecting the terminal portion of the sensor chip and the board-side terminal portion,
The pulse wave detection device, wherein the conductive member is arranged at a position that does not overlap with an edge of the top surface when seen in a plan view in the vertical direction.
請求項1〜5のいずれか1項記載の脈波検出装置と、
前記圧脈波センサによって検出された圧脈波に基づいて生体情報を算出する生体情報算出部と、を備える生体情報測定装置。
The pulse wave detection device according to claim 1.
A biological information measuring device, comprising: a biological information calculation unit that calculates biological information based on the pressure pulse wave detected by the pressure pulse wave sensor.
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Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP6777535B2 (en) * 2016-12-28 2020-10-28 オムロン株式会社 Sphygmomanometer and blood pressure measurement method and equipment
JP7124376B2 (en) * 2018-03-26 2022-08-24 セイコーエプソン株式会社 Biological information measuring device
KR102751479B1 (en) * 2018-07-06 2025-01-09 삼성전자주식회사 Apparatus and method for measuring bio-information
JP7193262B2 (en) * 2018-07-23 2022-12-20 ミネベアミツミ株式会社 tactile sensor
CN110255491A (en) * 2019-06-27 2019-09-20 中国科学院微电子研究所 MEMS pressure sensor encapsulating structure and packaging method
CN110403540A (en) * 2019-08-20 2019-11-05 珠海市一微半导体有限公司 Toning equipment and clean robot for the detection of ground medium
JPWO2023210216A1 (en) * 2022-04-28 2023-11-02
KR20250062179A (en) * 2023-10-30 2025-05-08 (주)파트론 Coupling Device for Assembling Stacked Photoplethysmography Sensor Packages

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS57168133A (en) * 1981-04-10 1982-10-16 Ricoh Elemex Corp Pressure wave sensor
JPH01117303U (en) * 1988-01-29 1989-08-08
JP2613622B2 (en) * 1988-05-16 1997-05-28 コーリン電子株式会社 Pulse wave detector
JP2863281B2 (en) * 1990-07-06 1999-03-03 コーリン電子株式会社 Contact pressure sensor
US5179956A (en) * 1990-07-06 1993-01-19 Colin Electronics Co., Ltd. Contact pressure sensor
US5797850A (en) * 1993-11-09 1998-08-25 Medwave, Inc. Method and apparatus for calculating blood pressure of an artery
JP3772691B2 (en) * 2001-05-09 2006-05-10 オムロンヘルスケア株式会社 Pulse wave detector
US20060195035A1 (en) * 2005-02-28 2006-08-31 Dehchuan Sun Non-invasive radial artery blood pressure waveform measuring apparatus system and uses thereof
US8777862B2 (en) * 2007-10-12 2014-07-15 Tensys Medical, Inc. Apparatus and methods for non-invasively measuring a patient's arterial blood pressure
JP5395484B2 (en) * 2009-03-25 2014-01-22 シチズンホールディングス株式会社 Mounting device
JP5195722B2 (en) * 2009-11-13 2013-05-15 オムロンヘルスケア株式会社 Electronic blood pressure monitor
JP5732692B2 (en) * 2010-08-02 2015-06-10 セイコーエプソン株式会社 Blood pressure detection device and blood pressure detection method
CN103565428B (en) * 2012-07-18 2015-12-09 株式会社日立制作所 Pulse detecting device and pulse detection method
JP2015080601A (en) * 2013-10-23 2015-04-27 セイコーエプソン株式会社 Pulse wave sensor and biological information measuring apparatus using the same
JP6256058B2 (en) * 2014-01-31 2018-01-10 オムロンヘルスケア株式会社 Pulse wave detector
CN204147018U (en) * 2014-03-28 2015-02-11 深圳市大富网络技术有限公司 A kind of arteriopalmus checkout gear, pressure sensor assembly, Intelligent spire lamella, intelligent watch and communication system
JP5780505B1 (en) * 2014-05-15 2015-09-16 株式会社アクトメディカルサービス Pulse wave and pressure detection application device, and blood vessel pulse wave measurement system
JP6212000B2 (en) * 2014-07-02 2017-10-11 株式会社東芝 Pressure sensor, and microphone, blood pressure sensor, and touch panel using pressure sensor

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US20190046051A1 (en) 2019-02-14
EP3453320B1 (en) 2023-12-13
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WO2017188093A1 (en) 2017-11-02
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