WO2016130098A1 - Transesophageal thermal tactile stimulation apparatus - Google Patents
Transesophageal thermal tactile stimulation apparatus Download PDFInfo
- Publication number
- WO2016130098A1 WO2016130098A1 PCT/TR2015/050169 TR2015050169W WO2016130098A1 WO 2016130098 A1 WO2016130098 A1 WO 2016130098A1 TR 2015050169 W TR2015050169 W TR 2015050169W WO 2016130098 A1 WO2016130098 A1 WO 2016130098A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- esophagus
- transesophageal
- balloon
- tactile stimulation
- stimulation apparatus
- Prior art date
Links
- 230000000638 stimulation Effects 0.000 title claims description 36
- 210000003238 esophagus Anatomy 0.000 claims abstract description 77
- 239000012530 fluid Substances 0.000 claims description 43
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 16
- 230000003247 decreasing effect Effects 0.000 claims 1
- 230000009747 swallowing Effects 0.000 abstract description 10
- 208000019505 Deglutition disease Diseases 0.000 abstract description 5
- 230000007246 mechanism Effects 0.000 abstract description 4
- 210000000133 brain stem Anatomy 0.000 abstract description 3
- 230000002232 neuromuscular Effects 0.000 abstract description 3
- 230000004936 stimulating effect Effects 0.000 abstract description 3
- 230000003213 activating effect Effects 0.000 abstract description 2
- 230000001447 compensatory effect Effects 0.000 abstract description 2
- 230000001054 cortical effect Effects 0.000 abstract description 2
- 210000000653 nervous system Anatomy 0.000 abstract description 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 6
- 238000011282 treatment Methods 0.000 description 5
- 208000006011 Stroke Diseases 0.000 description 4
- 208000035475 disorder Diseases 0.000 description 4
- 238000000034 method Methods 0.000 description 4
- 206010008190 Cerebrovascular accident Diseases 0.000 description 3
- 230000004899 motility Effects 0.000 description 3
- 210000003169 central nervous system Anatomy 0.000 description 2
- 230000006378 damage Effects 0.000 description 2
- 201000010099 disease Diseases 0.000 description 2
- 210000003205 muscle Anatomy 0.000 description 2
- 230000011514 reflex Effects 0.000 description 2
- 208000005872 Diffuse Esophageal Spasm Diseases 0.000 description 1
- 208000000289 Esophageal Achalasia Diseases 0.000 description 1
- 206010030136 Oesophageal achalasia Diseases 0.000 description 1
- 206010030181 Oesophageal perforation Diseases 0.000 description 1
- 206010060696 Presbyoesophagus Diseases 0.000 description 1
- 206010039710 Scleroderma Diseases 0.000 description 1
- 201000000621 achalasia Diseases 0.000 description 1
- 230000001154 acute effect Effects 0.000 description 1
- 230000006978 adaptation Effects 0.000 description 1
- 206010002022 amyloidosis Diseases 0.000 description 1
- 230000001055 chewing effect Effects 0.000 description 1
- 230000002595 cold damage Effects 0.000 description 1
- 230000008602 contraction Effects 0.000 description 1
- 230000003111 delayed effect Effects 0.000 description 1
- 230000001815 facial effect Effects 0.000 description 1
- 208000014674 injury Diseases 0.000 description 1
- 238000005259 measurement Methods 0.000 description 1
- 230000007659 motor function Effects 0.000 description 1
- 230000004118 muscle contraction Effects 0.000 description 1
- 210000005036 nerve Anatomy 0.000 description 1
- 230000000926 neurological effect Effects 0.000 description 1
- 230000035764 nutrition Effects 0.000 description 1
- 235000016709 nutrition Nutrition 0.000 description 1
- 210000000056 organ Anatomy 0.000 description 1
- 230000002093 peripheral effect Effects 0.000 description 1
- 210000003800 pharynx Anatomy 0.000 description 1
- 230000008439 repair process Effects 0.000 description 1
- 230000009885 systemic effect Effects 0.000 description 1
- 238000002560 therapeutic procedure Methods 0.000 description 1
- 230000008733 trauma Effects 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F7/00—Heating or cooling appliances for medical or therapeutic treatment of the human body
- A61F7/12—Devices for heating or cooling internal body cavities
- A61F7/123—Devices for heating or cooling internal body cavities using a flexible balloon containing the thermal element
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F7/00—Heating or cooling appliances for medical or therapeutic treatment of the human body
- A61F7/12—Devices for heating or cooling internal body cavities
- A61F2007/126—Devices for heating or cooling internal body cavities for invasive application, e.g. for introducing into blood vessels
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2210/00—Anatomical parts of the body
- A61M2210/10—Trunk
- A61M2210/1042—Alimentary tract
- A61M2210/105—Oesophagus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M25/00—Catheters; Hollow probes
- A61M25/10—Balloon catheters
- A61M25/1002—Balloon catheters characterised by balloon shape
Definitions
- Invention is about an apparatus which contributes the neuromuscular compensatory mechanisms to develop, to regulate or to heal by activating the swallowing centers at brain stem and cortical level and stimulating esophagus covered with a rich nervous system network in patients who have swallowing disorder.
- stimulation is sent to the swallowing center in brain stem by stimulating the front facial arches by cooled laryngeal mirrors. Stimulations are underwent adaptation in that place and ignites the swallowing reflex.
- Esophagus motor function disorders achalasia, diffuse esophageal spasm
- motility disorders because of systemic diseases (scleroderma, amyloidosis, parkinson, etc.)
- motility disorders because of old age (presbyesophagus)
- swallowing problems because of esophagus in apoplexy patients can be counted in diseases concern esophagus which can be treated with thermal stimulations.
- the Invention is a transesophageal thermal tactile stimulation device in a form of a nasogastric tube and comprising radio-opaque ruler markers on it to determine the level of entrance to the esophagus.
- the nasogastric tube comprises at least one balloon that is coiled around and expandable to 1 -2 centimeters. The first balloon is properly placed to stimulate the upper esophagus section, the second balloon is properly placed to stimulate the central esophagus section and the third balloon is properly placed to stimulate the lower esophagus section separately or all together. Developing of compensation mechanism or regulation is achieved by giving cold and hot water simultaneously in to the three canals or one by one. That thermal stimulation of the receptors in esophagus causes central nervous system to be stimulated.
- Invention is a transesophageal thermal tactile stimulation apparatus, comprising a nasogastric tube (1 ), a feeding entrance (1 .1 ), an upper esophagus fluid entrance (1 .2), a central esophagus fluid entrance (1 .3), a lower esophagus fluid entrance (1 .4), a fluid exit (1 .5), a fluid exit canal (1 .5.1 ), an inner balloon fluid exit canal (1 .5.2), a nasogastric tube exit (1 .6), an upper esophagus balloon (2), a central esophagus balloon (2.1 ), a lower esophagus balloon (3), an entrance temperature sensor (4), an inner temperature sensor (5), a pressure sensor (6), a software (7), an external water source (8).
- Transesophageal thermal tactile stimulation apparatus is designed like a nasogastric tube which comprises a nasogastric tube exit (1 .6) that enables the patient to be fed.
- the tube has a proper length and width for both children and adults.
- the nasogastric tube (1 ) comprises the upper esophagus balloon (2), the central esophagus balloon (2.1 ) and the lower esophagus balloon (3) which are coiled around the tube.
- the nasogastric tube (1 ) comprises radio-opaque ruler markers on it to determine the level of entrance to the esophagus.
- the nasogastric tube (1 ) comprises the upper esophagus balloon (2), the central esophagus balloon (2.1 ) and the lower esophagus balloon (3) which can expand maximum 2 centimeters when the fluid is injected in them and they are coiled around the tube.
- the upper esophagus balloon (2), the central esophagus balloon (2.1 ) and the lower esophagus balloon (3) are placed on the nasogastric tube (1 ) with at least 1 centimeter spaces between them and with at least one coil. That design enables to stimulate the upper esophagus, central esophagus and the lower esophagus sections separately or simultaneously.
- the upper esophagus balloon (2), the central esophagus balloon (2.1 ) and the lower esophagus balloon (3) are in a structure that can pass through the nose when they are deflated and they can also expand when the fluid is injected in them.
- the continuous flow of the injected fluid through the upper esophagus fluid entrance (1 .2), the central esophagus fluid entrance (1 .3) and the lower esophagus fluid entrance (1 .4) is important for the esophagus area which is wanted to be cooled or heated. For that reason, the fluid exit (1 .5) is designed for retaking the injected fluid.
- the fluid exit canal (1 .5) is hidden inside of the nasogastric tube (1 ).
- the entrance temperature sensor (4) and the inner temperature sensor (5) are used to see if the inner temperature of the esophagus is reached at desired level and to prevent hot and cold damages on patient.
- the information that comes from those temperature sensors provides to hold the inner esophagus temperature level stable and at desired level by controlling the flow temperature of the water with the software (7), which comes from the external water source (8).
- the external water source (8) that comprises the software (7), let the water temperature to be adjusted with the adjusting buttons on it to the desired temperature.
- the balloon shaped sections between the upper esophagus fluid entrance (1 .2), the central esophagus fluid entrance (1 .3), the lower esophagus fluid entrance (1 .4) and the fluid exit (1 .5) canals can expand without causing a trauma to the esophagus. Those balloons can also dilate.
- Developing of compensation mechanism or regulation is achieved by giving cold and hot water simultaneously in to the upper esophagus fluid entrance (1 .2), the central esophagus fluid entrance (1 .3), the lower esophagus fluid entrance (1 .4) or one by one. That thermal stimulation of the receptors in esophagus causes central nervous system to be stimulated Invention can be used in patients with acute stroke and esophagus motility disorder.
- the nasogastric tube is one of the primary methods of feeding in the patients with swallowing disorder. Because of the invention can be used as a nasogastric tube, an extra implementation of nasogastric tube to the patient will not be necessary. Patients can be fed and be treated with a single product. Besides, the invention can archive the measurements of patients' data and can physically report when it is needed or email to the desired email addresses with the software (7).
Landscapes
- Health & Medical Sciences (AREA)
- Vascular Medicine (AREA)
- Thermal Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Physics & Mathematics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Thermotherapy And Cooling Therapy Devices (AREA)
Abstract
Invention is about an apparatus which contributes the neuromuscular compensatory mechanisms to develop, to regulate or to heal by activating the swallowing centers at brain stem and cortical level and stimulating esophagus covered with a rich nervous system network in patients who have swallowing disorder.
Description
DESCRIPTION
TRANSESOPHAGEAL THERMAL TACTILE STIMULATION APPARATUS
TECHINAL FIELD
Invention is about an apparatus which contributes the neuromuscular compensatory mechanisms to develop, to regulate or to heal by activating the swallowing centers at brain stem and cortical level and stimulating esophagus covered with a rich nervous system network in patients who have swallowing disorder.
PRIOR TECHNIC
Swallowing difficulties are seen in %25-42 percentage of patients who have neurological problems or had acute apoplexy before. Also in old ages (65 and older) it has been stated that a disruption in a ratio of %8-16 has seen in the abilities like swallowing, chewing and nutrition. In the situations like this, additional to swallowing treatments, external electrical, thermal or radio frequency stimulations are applied to the problematic organs. As an example to the electrical stimulation treatment, Vitalstim Therapy is a form of neuromuscular electrical stimulation which is developed for the treatment of swallowing disorders and especially focuses the stimulation of pharyngeal, laryngeal and suprahyoid muscles. Current impulses cause the necessary contraction in peripheral motor nerves for a normal swallow. It repairs the muscle contractions. It retrains the affected muscles and make them contract properly. In the recent studies it had been shown that electrical stimulation of the pharynx is effective on swallowing in patients who had apoplexy. Thus, "Phagenyx" named system has been developed. That system has to be applied three times to the patient. Average cost of the system is five thousand Turkish Liras. Despite the fact that the system has positive results, its high cost limits the usage of that system in our country. Except of the electrical stimulation methods, thermal (hot-cold) tactile stimulation methods are used.
In patients who have a delayed swallowing reflex, stimulation is sent to the swallowing center in brain stem by stimulating the front facial arches by
cooled laryngeal mirrors. Stimulations are underwent adaptation in that place and ignites the swallowing reflex.
None of the above mentioned treatment methods can be used in treatment of swallowing disorders that concern esophagus. Esophagus motor function disorders (achalasia, diffuse esophageal spasm), motility disorders because of systemic diseases (scleroderma, amyloidosis, parkinson, etc.), motility disorders because of old age (presbyesophagus) and swallowing problems because of esophagus in apoplexy patients can be counted in diseases concern esophagus which can be treated with thermal stimulations.
BRIEF DESCRIPTION OF THE INVENTION
Invention is a transesophageal thermal tactile stimulation device in a form of a nasogastric tube and comprising radio-opaque ruler markers on it to determine the level of entrance to the esophagus. The nasogastric tube comprises at least one balloon that is coiled around and expandable to 1 -2 centimeters. The first balloon is properly placed to stimulate the upper esophagus section, the second balloon is properly placed to stimulate the central esophagus section and the third balloon is properly placed to stimulate the lower esophagus section separately or all together. Developing of compensation mechanism or regulation is achieved by giving cold and hot water simultaneously in to the three canals or one by one. That thermal stimulation of the receptors in esophagus causes central nervous system to be stimulated.
MEANINGS OF THE FIGURES
Figure 1 . Transesophageal Thermal Tactile Stimulation Apparatus Isometric
View (Balloons are inflated)
Figure 2. Transesophageal Thermal Tactile Stimulation Apparatus Isometric
View (Balloons are deflated)
Figure 3. Transesophageal Thermal Tactile Stimulation Apparatus Upper
View (Balloons are inflated)
Figure 4. Transesophageal Thermal Tactile Stimulation Apparatus Upper
View (Balloons are deflated)
Figure 5. Transesophageal Thermal Tactile Stimulation Apparatus Side
View (Balloons are inflated)
Figure 6. Transesophageal Thermal Tactile Stimulation Apparatus Side A-A
Section View
Figure 7. Transesophageal Thermal Tactile Stimulation Apparatus C
Detailed View
Figure 8. Transesophageal Thermal Tactile Stimulation Apparatus Section
View of the Inside of the Tube
Figure 9. Connection of the Tube and The External Water Source
Equivalents of indicated numbers are given below
1 . Nasogastric Tube
1 .1 . Feeding Entrance
1 .2. Upper Esophagus Fluid Entrance
1 .3. Central Esophagus Fluid Entrance
1 .4. Lower Esophagus Fluid Entrance
1 .5. Fluid Exit
1 .5.1 . Fluid Exit Canal
1 .5.2. Inner Balloon Fluid Exit Canal
1 .6. Nasogastric Tube Exit
2. Upper Esophagus Balloon
2.1 . Central Esophagus Balloon
3. Lower Esophagus Balloon
4. Entrance Temperature Sensor
5. Inner Temperature Sensor
6. Pressure Sensor
7. Software
8. External Water Source
DETAILED DESCRIPTION OF THE INVENTION
Invention is a transesophageal thermal tactile stimulation apparatus, comprising a nasogastric tube (1 ), a feeding entrance (1 .1 ), an upper esophagus fluid entrance (1 .2), a central esophagus fluid entrance (1 .3), a lower esophagus fluid entrance (1 .4), a fluid exit (1 .5), a fluid exit canal (1 .5.1 ),
an inner balloon fluid exit canal (1 .5.2), a nasogastric tube exit (1 .6), an upper esophagus balloon (2), a central esophagus balloon (2.1 ), a lower esophagus balloon (3), an entrance temperature sensor (4), an inner temperature sensor (5), a pressure sensor (6), a software (7), an external water source (8).
Transesophageal thermal tactile stimulation apparatus is designed like a nasogastric tube which comprises a nasogastric tube exit (1 .6) that enables the patient to be fed. The tube has a proper length and width for both children and adults. The nasogastric tube (1 ) comprises the upper esophagus balloon (2), the central esophagus balloon (2.1 ) and the lower esophagus balloon (3) which are coiled around the tube. The nasogastric tube (1 ) comprises radio-opaque ruler markers on it to determine the level of entrance to the esophagus.
The nasogastric tube (1 ) comprises the upper esophagus balloon (2), the central esophagus balloon (2.1 ) and the lower esophagus balloon (3) which can expand maximum 2 centimeters when the fluid is injected in them and they are coiled around the tube. The upper esophagus balloon (2), the central esophagus balloon (2.1 ) and the lower esophagus balloon (3) are placed on the nasogastric tube (1 ) with at least 1 centimeter spaces between them and with at least one coil. That design enables to stimulate the upper esophagus, central esophagus and the lower esophagus sections separately or simultaneously. The upper esophagus balloon (2), the central esophagus balloon (2.1 ) and the lower esophagus balloon (3) are in a structure that can pass through the nose when they are deflated and they can also expand when the fluid is injected in them. The continuous flow of the injected fluid through the upper esophagus fluid entrance (1 .2), the central esophagus fluid entrance (1 .3) and the lower esophagus fluid entrance (1 .4) is important for the esophagus area which is wanted to be cooled or heated. For that reason, the fluid exit (1 .5) is designed for retaking the injected fluid. The fluid exit canal (1 .5) is hidden inside of the nasogastric tube (1 ). It carries the taken fluid from inner balloon fluid exit canal (1 .5.2), which is located in every balloon, to the fluid exit (1 .5). Thus, the continuous fluid flow can be provided for every balloon when it is needed. The fluid, which is injected through the upper esophagus fluid entrance (1 .2), the central esophagus fluid entrance (1 .3) and the lower esophagus fluid entrance
(1 .4) placed upper section of the apparatus, completes its continuous flow by passing through the fluid exit canal (1 .5.1 ) placed in the nasogastric tube (1 ).
The entrance temperature sensor (4) and the inner temperature sensor (5) are used to see if the inner temperature of the esophagus is reached at desired level and to prevent hot and cold damages on patient. The information that comes from those temperature sensors provides to hold the inner esophagus temperature level stable and at desired level by controlling the flow temperature of the water with the software (7), which comes from the external water source (8). The external water source (8) that comprises the software (7), let the water temperature to be adjusted with the adjusting buttons on it to the desired temperature.
With at least one pressure sensor (6) placed upon the upper esophagus balloon (2), the central esophagus balloon (2.1 ) and the lower esophagus balloon (3), the complete touch of the tubes to the esophagus lumen is detected. Incoming water pressure and outgoing water pressure is controlled with the software (7). Thus prevents the occurring of complications like narrowness and perforation of esophagus because of pressure damages.
There are studies in the literature about the balloons that are used for expanding the esophagus. But the main purpose of those studies is to expand the narrowness in esophagus. Those balloons have a single canal and they aim to expand the narrowness. Using them in a normal esophagus can harm the patient and they also cannot provide the continuous water flow with necessary temperature to stimulate the esophagus.
In the transesophageal thermal tactile stimulation apparatus, which is subject to invention, the balloon shaped sections between the upper esophagus fluid entrance (1 .2), the central esophagus fluid entrance (1 .3), the lower esophagus fluid entrance (1 .4) and the fluid exit (1 .5) canals, can expand without causing a trauma to the esophagus. Those balloons can also dilate.
Developing of compensation mechanism or regulation is achieved by giving cold and hot water simultaneously in to the upper esophagus fluid entrance (1 .2), the central esophagus fluid entrance (1 .3), the lower esophagus fluid entrance (1 .4) or one by one. That thermal stimulation of the receptors in esophagus causes central nervous system to be stimulated
Invention can be used in patients with acute stroke and esophagus motility disorder. The nasogastric tube is one of the primary methods of feeding in the patients with swallowing disorder. Because of the invention can be used as a nasogastric tube, an extra implementation of nasogastric tube to the patient will not be necessary. Patients can be fed and be treated with a single product. Besides, the invention can archive the measurements of patients' data and can physically report when it is needed or email to the desired email addresses with the software (7).
Claims
1. A transesophageal thermal tactile stimulation apparatus, comprising; a nasogastric tube (1 ), a feeding entrance (1 .1 ), an upper esophagus fluid entrance (1 .2), a central esophagus fluid entrance (1 .3), a lower esophagus fluid entrance (1 .4), a fluid exit (1 .5), a fluid exit canal (1 .5.1 ), an inner balloon fluid exit canal (1 .5.2), a nasogastric tube exit (1 .6), an upper esophagus balloon (2), a central esophagus balloon (2.1 ), a lower esophagus balloon (3), an entrance temperature sensor (4), an inner temperature sensor (5), a pressure sensor (6), a software (7), an external water source (8).
2. The transesophageal thermal tactile stimulation apparatus of claim 1 , wherein the upper esophagus balloon (2) is coiled around the nasogastric tube (1 ) at least one centimeter spaces between them and with at least one coil.
3. The transesophageal thermal tactile stimulation apparatus of claim 2, wherein the upper esophagus balloon (2) has a width of two centimeters maximum when it is filled.
4. The transesophageal thermal tactile stimulation apparatus of claim 1 , wherein the central esophagus balloon (2.1 ) is coiled around the nasogastric tube (1 ) at least one centimeter spaces between them and with at least one coil.
5. The transesophageal thermal tactile stimulation apparatus of claim 4, wherein the central esophagus balloon (2.1 ) has a width of two centimeters maximum when it is filled.
6. The transesophageal thermal tactile stimulation apparatus of claim 1 , wherein the lower esophagus balloon (3) is coiled around the nasogastric tube (1 ) at least one centimeter spaces between them and with at least one coil.
7. The transesophageal thermal tactile stimulation apparatus of claim 6, wherein the lower esophagus balloon (3) has a width of two centimeters maximum when it is filled.
8. The transesophageal thermal tactile stimulation apparatus of claim 1 , wherein the software (7) decides the water temperature to be increased or decreased regarding to information gathered from entrance temperature sensor (4).
9. The transesophageal thermal tactile stimulation apparatus of claim 1 , wherein the software (7) sends a warning to the user regarding to information gathered from pressure sensor (6).
"lO.The transesophageal thermal tactile stimulation apparatus of claim 1 , wherein the user can adjust the temperature and the intensity of water by the external water source (8)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
TR201501533 | 2015-02-10 | ||
TR2015/01533 | 2015-02-10 |
Publications (1)
Publication Number | Publication Date |
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WO2016130098A1 true WO2016130098A1 (en) | 2016-08-18 |
Family
ID=54704059
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PCT/TR2015/050169 WO2016130098A1 (en) | 2015-02-10 | 2015-11-11 | Transesophageal thermal tactile stimulation apparatus |
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Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20010053920A1 (en) * | 2000-03-27 | 2001-12-20 | Wilson-Cook Medical Inc. | Apparatus for measuring esophageal sphincter compliance |
EP1264613A2 (en) * | 2000-01-24 | 2002-12-11 | Stuart D. Edwards | Shrinkage of dilations in the body |
WO2003020124A2 (en) * | 2001-09-06 | 2003-03-13 | Aalborg Universitet | Method an apparatus for stimulating a bodily hollow system and method and apparatus for measuring reactions to stimuli of such system |
US20080027358A1 (en) * | 2004-06-30 | 2008-01-31 | Ditens A/S | Morphometry of a Bodily Hollow System |
US20080097374A1 (en) * | 2006-08-07 | 2008-04-24 | Korleski Joseph E | Inflatable shaped balloons |
-
2015
- 2015-11-11 WO PCT/TR2015/050169 patent/WO2016130098A1/en active Application Filing
Patent Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1264613A2 (en) * | 2000-01-24 | 2002-12-11 | Stuart D. Edwards | Shrinkage of dilations in the body |
US20010053920A1 (en) * | 2000-03-27 | 2001-12-20 | Wilson-Cook Medical Inc. | Apparatus for measuring esophageal sphincter compliance |
WO2003020124A2 (en) * | 2001-09-06 | 2003-03-13 | Aalborg Universitet | Method an apparatus for stimulating a bodily hollow system and method and apparatus for measuring reactions to stimuli of such system |
US20080027358A1 (en) * | 2004-06-30 | 2008-01-31 | Ditens A/S | Morphometry of a Bodily Hollow System |
US20080097374A1 (en) * | 2006-08-07 | 2008-04-24 | Korleski Joseph E | Inflatable shaped balloons |
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